Dimethyl Methoxybenzodihydropyran Palmitate Powder

Dimethyl Methoxybenzodihydropyran Palmitate Powder

Dimethyl Methoxybenzodihydropyran Palmitate Powder
1. Specification: 98.0% – 102.0% (on dried basis)
2. Sample: Sample Available
3. Test method: HPLC / GC / Titration
4. Synonyms: Dimethylmethoxybenzodihydropyran palmitate, DMMBDPP, Chromabright™ (INCI name: Dimethylmethoxychromanyl Palmitate)
5. Appearance: Fine, free‑flowing white to pale yellow crystalline powder; faint characteristic odor
6. Particle size: >95% pass 80 mesh
7. MOQ: 1 KG
8. Package: 1kg/foil bag (light-protected), 25kgs/drum
9. Certificate: HACCP, ISO 22000, GMP, Kosher (available upon request; HALAL varies by batch)
10. Molecular Formula: C₂₈H₄₄O₄
11. CAS number: 146450-86-6
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Description

 

Dimethyl Methoxybenzodihydropyran Palmitate Powder

Let's be honest. The name is a mouthful. Dimethyl methoxybenzodihydropyran palmitate sounds like something a chemist muttered in a dream. Let's just call it DMMBDPP - its much more manageable nickname.

So, what is this molecule with the unpronounceable name? It's a smart brightener. Not a bleach, not a scrub, not a laser. It's a tiny, lipophilic spy that infiltrates your skin cells and talks directly to the melanin production factory - specifically, the MC1R receptor (melanocortin 1 receptor).

The "Light Switch" Mechanism: Most brighteners (like hydroquinone or kojic acid) are brute-force weapons. They poison tyrosinase, the enzyme that makes melanin. It works, but it often irritates the skin and can cause inflammation. DMMBDPP is different. It's a mimic. It looks like alpha‑melanocyte stimulating hormone (α‑MSH) - the natural molecule that tells your skin to tan - but it's a fake ID. It binds to the MC1R receptor, takes up the parking space, and… does nothing. It doesn't turn on the melanin factory. It just blocks the real signal.

The Palmitate Tail: That's the stealth cloak. The palmitate group makes the molecule highly lipophilic, meaning it penetrates the stratum corneum easily and stays in the skin longer. It's not washed off. It's not metabolized quickly. It sits in the membrane, working quietly for hours.

The Chromabright™ Connection: If you've been in the cosmetic chemistry world, you might know this molecule under its trade name, Chromabright™. It's a patented, clinically proven brightener. But patents expire. And now, generic DMMBDPP is here - same molecule, same performance, better price.

📦 Storage Note: Low melting point (58–65°C). Store below 30°C in a cool, dry place. Protect from light (amber packaging recommended). Do not expose to high heat during shipping or storage.

Specification: 98.0% – 102.0% (on dried basis)
Sample: Sample Available
Test method: HPLC / GC / Titration
Synonyms: Dimethylmethoxybenzodihydropyran palmitate, DMMBDPP, Chromabright™ (INCI: Dimethylmethoxychromanyl Palmitate)
MOQ: 1 KG  |  Package: 1kg/foil bag (light-protected), 25kgs/drum
Certificate: HACCP, ISO 22000, GMP, Kosher (available upon request)
Molecular Formula: C₂₈H₄₄O₄  |  CAS: 146450-86-6

Dimethyl Methoxybenzodihydropyran Palmitate Powder
Product Characteristics
 
🎯

Mechanism of Action

MC1R antagonist - blocks the α‑MSH signal that triggers melanin production. No cytotoxicity.
⚗️

Purity

≥98% - high-purity synthetic active.
💧

Solubility

Lipophilic - soluble in oils, esters, ethanol. Insoluble in water.
🌡️

Melting Point

58 – 65°C (waxy solid; store below 30°C).
📏

Particle Size

>95% pass 80 mesh; micronized available.
🏭

GMP Manufacturing

Multi‑step organic synthesis, purified by recrystallization and column chromatography.

COA (Certificate of Analysis)

>

Benefits of DMMBDPP Powder

01MC1R Antagonist - The Smart Brightener

DMMBDPP binds to the melanocortin 1 receptor without activating it, blocking the natural α‑MSH signal that triggers melanin production. Less melanin, no cytotoxicity.

02No Irritation, No Inflammation

Unlike hydroquinone or kojic acid, DMMBDPP does not poison tyrosinase or damage melanocytes. Clinical studies show no irritation, sensitization, or phototoxicity.

03Reduces Post-Inflammatory Hyperpigmentation (PIH)

Clinically effective for dark spots from acne, eczema, and injury. Reduces melanin transfer to keratinocytes - natural, even brightening.

04Lipophilic - Excellent Skin Penetration

The palmitate tail makes the molecule highly lipophilic, penetrating the stratum corneum easily and staying in the skin longer. Not washed off, not quickly metabolized.

05Anti-Inflammatory Bonus

DMMBDPP inhibits prostaglandin E2 (PGE2), an inflammatory mediator involved in UV‑induced redness and melanogenesis. Less inflammation = less PIH.

06Safe for All Skin Types (I–VI)

Non‑irritating, non‑sensitizing, non‑comedogenic. Particularly useful for darker skin types (IV–VI) who are prone to PIH and cannot tolerate hydroquinone.

Application Fields

Skincare & Cosmeceuticals (Hero Application): Brightening serums (0.2–0.5%), post-acne mark treatments (0.2–0.5%), melasma creams (0.5–1.0%), anti‑aging brightening creams, UV after‑sun lotions (0.2–0.3%).
OEM Finished Products: Brightening serums, dark spot correctors, even tone creams, antioxidant brightening lotions, liposomal brightening ampoules, post-acne recovery gels - full custom manufacturing available.

Production Process

Production process of DMMBDPP

Product Quality Advantage

≥98% Purity – High-purity synthetic active.

MC1R Antagonist – Smart brightening mechanism, no cytotoxicity.

Low Heavy Metals – Pb <0.3 ppm, As <0.5 ppm.

Lipophilic – Excellent skin penetration.

Stable (When Stored Properly) – 24 months shelf life.

cGMP Certified – Full traceability and documentation.

GMP Workshop
Quality Control Lab

Annual Capacity: 1,500 Tons | 15+ years of specialty organic synthesis

Professional ODM/OEM Services

We provide full OEM/ODM manufacturing for finished products using DMMBDPP as the active brightening ingredient.

① Finished Skincare Products
Brightening Serums (0.2–0.5% DMMBDPP), Dark Spot Correctors (+ tranexamic acid, niacinamide), Even Tone Creams, Liposomal Brightening Ampoules, Post-Acne Recovery Gels.

② Formulation Support
Solubilization of lipophilic DMMBDPP in water‑based serums (use solubilizers or pre‑dissolve in ethanol/propanediol). Emulsion formulation (O/W or W/O). Stability testing (monitor for crystal formation).

③ Additional Services
Third‑party certification (Kosher), regulatory documentation (EU Cosmetic Regulation compliance), custom blend development (DMMBDPP + tranexamic acid + niacinamide).

Export Certificates

Certificates HACCP ISO GMP Kosher

Why choose us

XI'AN LANDNUTRA CO., LTD. – Your Trusted Manufacturer of Antioxidant & Functional Ingredients. Rooted in Quality, Driven by Expertise, Committed to Health and Excellence.

Strong Production Capability: Annual capacity 1,500 tons. 15+ years experience, own facility.
Leading Service: ONE-STOP OEM/ODM from pre-sales to after-sales.
Quality Assurance: CQC-certified enterprise, purity embedded in every process.
Broad Market: Botanical Extracts, Cosmetic Ingredients, Functional Ingredients.

15+ years of specialty organic synthesis. cGMP‑certified facilities. Full in‑house OEM/ODM capabilities for brightening skin care. Regulatory documentation for global markets. Batch‑specific COA including assay, melting point, related substances, and heavy metals. Technical support for formulation (solubilization, stabilization, emulsification).

FAQ

Q1: Is DMMBDPP the same as Chromabright™?
A: Yes, chemically. Chromabright™ is the brand name. Patents have expired in some regions, allowing generic production. Our DMMBDPP is chemically identical. Check local patent status before commercializing.
Q2: Is this a bleaching agent?
A: No. Bleaching agents (like hydroquinone) are cytotoxic to melanocytes. DMMBDPP simply reduces melanin synthesis without killing cells. The result is a natural, even skin tone - not a pale, unnatural white.
Q3: How long does it take to see results?
A: Typically 4–8 weeks of daily use. Brightening is gradual, not dramatic. This is a feature - no risk of over‑bleaching or uneven spots.
Q4: Can DMMBDPP be used with retinol?
A: Yes. They work well in the same routine (separate products or formulated together with proper stabilization). DMMBDPP is compatible with most cosmetic ingredients except strong acids (pH <3.5) and strong oxidizing agents.
Q5: Does DMMBDPP work on all skin types?
A: Yes. It is non‑irritating and non‑sensitizing, suitable for all Fitzpatrick skin types (I–VI). It is particularly useful for darker skin types prone to PIH who cannot tolerate hydroquinone.
Q6: Is DMMBDPP safe during pregnancy?
A: Topical use at cosmetic concentrations (0.2–0.5%) is generally considered safe, as systemic absorption is very low. However, consult a healthcare provider. No specific safety studies are available.
Q7: Why does the powder have a low melting point?
A: The palmitate ester is a long, waxy chain. Store below 30°C. Do not expose to high heat during shipping or storage. The powder is milled but will melt if overheated.
Q8: How should I formulate with DMMBDPP?
A: Pre‑dissolve DMMBDPP in the oil phase (heat to 60–65°C). For water‑based serums, use a solubilizer (polysorbate 20, PEG-40 hydrogenated castor oil) or pre‑dissolve in a small amount of ethanol. We provide formulation guidelines.
Q9: What is the shelf life of DMMBDPP powder?
A: 24 months in original sealed, light‑protected container under cool, dry conditions (≤25°C, ≤60% RH). Once opened, use within 12 months. Amber packaging is essential.
Q10: Is DMMBDPP natural?
A: No. It is fully synthetic. For "natural" or "clean" beauty brands, this may not be suitable. However, it is non‑toxic, non‑irritating, and has excellent safety data.
Q11: Does DMMBDPP provide any UV protection?
A: Minimal. It has a weak absorption peak in the UVB range (290–310 nm), but it is not approved as a sunscreen filter. Always recommend SPF 30+ separately.
Q12: Can I use DMMBDPP with vitamin C (L‑ascorbic acid)?
A: Be careful with pH. L‑ascorbic acid requires pH <3.5, which is below the optimal pH for DMMBDPP (pH 4–7). Consider using a vitamin C derivative (sodium ascorbyl phosphate, tetrahexyldecyl ascorbate) that is stable at higher pH.

 

Test Item Specification (Cosmetic Grade) Test Result Conclusion
Appearance White to pale yellow crystalline powder Conforms Pass
Assay (HPLC) 98.0% – 102.0% 99.4% Pass
Melting Point 58 – 65°C 62°C Pass
Water Content (KF) ≤1.0% 0.3% Pass
Residue on Ignition ≤0.2% 0.07% Pass
Lead (Pb) ≤1.0 ppm <0.3 ppm Pass
Arsenic (As) ≤1.0 ppm <0.5 ppm Pass
Related Substances (HPLC) ≤2.0% total 0.8% Pass
Total Plate Count ≤1,000 cfu/g <100 cfu/g Pass
E. Coli / Salmonella Negative Negative Pass

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