Best K2 MK-7 Gold Standard

Best K2 MK-7 Gold Standard

Best K2 MK-7 Powder
1. Specification: 98.0% – 102.0% (HPLC, on dried basis)
2. Sample: Sample Available
3. Test method: HPLC / LC-MS / USP method
4. Synonyms: Menaquinone-7, MK-7, Vitamin K2(35), all-trans-Menaquinone-7
5. Appearance: Pale yellow to white crystalline powder
6. Particle size: >95% pass 80 mesh
7. MOQ: 1 KG
8. Package: 1kg/foil bag (light-protected, inert gas flushed), 25kgs/drum
9. Certificate: HACCP, ISO 22000, GMP, HALAL (available upon request), Kosher (available upon request)
10. Molecular Formula: C₄₆H₆₄O₂
11. CAS number: 2124-57-4
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Description

 

Best K2 MK-7 Powder

Best K2 MK-7 Powder represents the pinnacle of vitamin K2 ingredients-a premium, highly purified menaquinone-7 (MK-7) produced through a controlled, natural fermentation process. As the most bioavailable and longest-acting form of vitamin K2, MK-7 is widely regarded as the gold standard for supporting bone health and cardiovascular function.

🦴 The "Calcium Director" Mechanism: MK-7 activates two essential vitamin K-dependent proteins that regulate calcium metabolism: Osteocalcin (directs calcium into bone tissue, supporting bone mineralization) and Matrix Gla-Protein (MGP) (prevents calcium deposition in blood vessels, protecting against vascular calcification).

Superior Bioavailability – The MK-7 Advantage: Unlike vitamin K1 (half-life ~1.5 hours) or MK-4 (requires milligram-level daily doses), MK-7 has an extended half-life of approximately 3 days. This allows for once-daily dosing at microgram levels (45–120 mcg/day) while maintaining sustained biological activity.

Clinically Supported & Trusted: Best K2 MK-7 is backed by a robust portfolio of clinical research, including multiple human trials published in peer-reviewed journals. These studies demonstrate its efficacy in supporting bone mineral density in post-menopausal women, maintaining bone health in middle-aged adults, and supporting healthy blood vessel elasticity.

🌡️ Storage Note: MK-7 is highly sensitive to light and heat. Store in the original sealed container, protected from light. Recommended storage at -20°C for long-term stability; 2–8°C for short-term.
⚠️ Important Safety Note: Vitamin K can interfere with anticoagulant medications (such as warfarin). Patients taking blood thinners should consult their healthcare provider before supplementation.

Specification: 98.0% – 102.0% (HPLC, on dried basis)
Sample: Sample Available
Test method: HPLC / LC-MS / USP method
Synonyms: Menaquinone-7, MK-7, Vitamin K2(35), all-trans-Menaquinone-7
MOQ: 1 KG  |  Package: 1kg/foil bag (light-protected, inert gas flushed), 25kgs/drum
Certificate: HACCP, ISO 22000, GMP, HALAL (available upon request), Kosher (available upon request)
Molecular Formula: C₄₆H₆₄O₂  |  CAS: 2124-57-4

Best K2 MK-7 Powder
Product Characteristics
 
🧂

Appearance

Pale yellow to white crystalline powder; odorless.
⚗️

Purity

98.0% – 102.0% (HPLC) - ultra-high purity.

Half-Life

~3 days - sustained activity, once-daily dosing.
💧

Solubility

Fat-soluble; soluble in oils; insoluble in water.
🔬

Source

Natural fermentation (Bacillus subtilis natto) - non-GMO.
🏭

GMP Manufacturing

Controlled fermentation with full traceability.

COA (Certificate of Analysis)

Note: Specifications vary by grade. This COA represents a typical high-purity (>99%) crystalline grade.

Test Item Specification Test Result Conclusion
Appearance Pale yellow to white crystalline powder Conforms Pass
Assay (HPLC) 98.0% – 102.0% 99.4% Pass
Identification (HPLC/LC-MS) Conforms to reference standard Conforms Pass
Water Content (KF) ≤1.0% 0.4% Pass
Heavy Metals (as Pb) ≤10 ppm <2 ppm Pass
Lead (Pb) ≤0.5 mg/kg <0.3 mg/kg Pass
Total Plate Count ≤1,000 CFU/g <100 CFU/g Pass
E. Coli / Salmonella Negative Negative Pass

Benefits of Best K2 MK-7 Powder

01Superior Calcium Metabolism Support

MK-7 activates osteocalcin, the primary non-collagen protein in bone that locks calcium into the skeletal structure. This mechanism supports bone mineralization and helps maintain bone density, particularly important for post-menopausal women and aging adults.

02Cardiovascular Protection

MK-7 activates Matrix Gla-Protein (MGP), which prevents calcium deposition in arterial walls, helping to maintain vascular elasticity and healthy circulation. This dual action-building bone while protecting arteries-is unique to vitamin K2.

03Extended Half-Life – Sustained Activity

With a half-life of approximately 3 days, Best K2 MK-7 provides prolonged biological activity compared to vitamin K1 (1.5 hours) or MK-4. Allows for convenient once-daily dosing at lower microgram levels.

04Clinically Researched Efficacy

Supported by a robust portfolio of well-controlled human clinical trials. Research demonstrates MK-7 supports healthy bone mineral density, maintains bone health, supports proper calcium metabolism in children, and promotes healthy blood vessel elasticity.

05Natural, Fermentation-Derived Quality

Sourced from natto fermentation using Bacillus subtilis natto. Naturally derived, free from chemical synthesis, fully traceable, clean-label, and vegan-friendly.

06Versatile Application Flexibility

Available in high-purity crystalline (>99%), standardized (0.2%–2.0%), and microencapsulated forms. Suitable for capsules, softgels, tablets, powder blends, gummies, and functional foods.

Application Fields

Dietary Supplements (Hero Application): Capsules & softgels (45–120 mcg), tablets, powder blends & stick packs, gummies & chewables, multivitamin & mineral blends (with Vitamin D3 and Calcium).
Functional Foods & Beverages: Fortified beverages, nutrition bars.
Cosmetics & Personal Care: Skin care (face cream, hand cream, body lotion).
OEM Finished Products: Softgels, bone support formula, cardiovascular powder sticks, gummies, custom bone health blends - full custom manufacturing available.

Production Process

Production process of Best K2 MK-7

Process: Bacillus subtilis natto fermentation → multi-stage extraction & purification → concentration & standardization → gentle drying → milling & sieving → QC testing → inert gas packaging.

Product Quality Advantage

98.0% – 102.0% Purity – Ultra-high purity crystalline grade.

~3 Day Half-Life – Sustained biological activity.

Natural Fermentation – Non-GMO Bacillus subtilis natto.

Low Heavy Metals – Pb <0.3 mg/kg.

Clinically Researched – Backed by human trials.

cGMP Certified – Full traceability and documentation.

Fermentation Facility
Quality Control Lab

Annual Capacity: 1,500 Tons | 15+ years of lipid-soluble vitamin expertise

Professional ODM/OEM Services

We provide full OEM/ODM manufacturing for finished products using Best K2 MK-7 as the active ingredient - from concept to commercial delivery, all under one roof.

① Finished Dosage Forms
Capsules & Softgels: 45 mcg, 90 mcg, 120 mcg; custom carrier oils.
Tablets: Direct compression; round/oval; debossing.
Chews & Gummies: Custom flavors, sugar‑free options.
Powder Blends: Stick packs, tubs; with Vitamin D3, Calcium, Magnesium.
Cosmetics: Serums, creams, lotions.
Bars: Protein bars, snack bars.

② Combination Options
MK-7 + Vitamin D3 + Calcium (bone health), MK-7 + Omega-3 (cardiovascular), MK-7 + Magnesium (mineral support).

③ Additional Services
Flavor development, third‑party certification (NSF, Informed Sport, Kosher, HALAL), stability testing (light protection), regulatory documentation.

📧 Email: wangjing@landnutra.com

📱 WhatsApp: +86 18092657549

All backed by LANDNUTRA's quality assurance - full GMP, Halal, Kosher, COA certification and complete traceability from sourcing to finished product.

Export Certificates

Certificates HACCP ISO GMP Halal Kosher

Why choose us

XI'AN LANDNUTRA CO., LTD. – Your Trusted Manufacturer of Functional Ingredients. Rooted in Quality, Driven by Expertise, Committed to Health and Excellence.

Strong Production Capability: Annual capacity 1,500 tons. 15+ years experience, own facility.
Leading Service: ONE-STOP OEM/ODM from pre-sales to after-sales.
Quality Assurance: CQC-certified enterprise, purity embedded in every process.
Broad Market: Botanical Extracts, Cosmetic Ingredients, Functional Ingredients.

15+ years of experience in functional ingredients and lipid-soluble vitamins. Vertically integrated from raw material sourcing to finished goods manufacturing. Batch‑specific COA including HPLC assay, heavy metals, water content, and microbial limits. Technical support for formulation and stability.

FAQ

Q1: What makes Best K2 MK-7 the "gold standard" of vitamin K2?
A: Best K2 MK-7 is the most bioavailable and longest-acting form of vitamin K2. Unlike vitamin K1 (short half-life) or MK-4 (requires milligram doses), MK-7 has a half-life of approximately 3 days and provides sustained activity at microgram doses. It is produced through natural fermentation using Bacillus subtilis natto, yielding a pure, natural all-trans menaquinone-7 that matches the compound found in natto.
Q2: What is the recommended daily dose?
A: Typical supplemental doses range from 45 mcg to 120 mcg per day. Clinical studies have used 800 mcg/day for specific bone health applications. Always consult a healthcare provider for personalized recommendations.
Q3: How does MK-7 compare to vitamin K1?
A: MK-7 achieves significantly higher and more stable blood levels than vitamin K1. While vitamin K1 has a half-life of approximately 1.5 hours and is primarily involved in blood clotting, MK-7 has a half-life of approximately 3 days and directs calcium to bones while protecting arteries.
Q4: Is Best K2 MK-7 vegan?
A: Yes. Our MK-7 is produced via bacterial fermentation (Bacillus subtilis natto) using non-GMO soy-based substrates. It does not contain any animal-derived components.
Q5: How should Best K2 MK-7 powder be stored?
A: Store in the original sealed container, protected from light, under cool, dry conditions. For long-term stability, store at -20°C. MK-7 is highly sensitive to light and heat. Once opened, use within 6 months and keep container tightly sealed.
Q6: Can Best K2 MK-7 be used in clear liquid supplements?
A: No. MK-7 is fat-soluble and insoluble in water. For aqueous applications, use microencapsulated or emulsified forms. It is best suited for softgels, capsules, tablets, and oil-based formulations.
Q7: What is the shelf life?
A: 24–36 months in original sealed container under recommended storage conditions. Stability is enhanced by light-protected packaging and proper storage.
Q8: Does Best K2 MK-7 interact with blood thinners?
A: Yes. Vitamin K can interfere with anticoagulant medications (such as warfarin). Patients taking blood thinners should consult their healthcare provider before supplementation.
Q9: Can MK-7 be combined with Vitamin D3 and Calcium?
A: Yes - this is a classic and synergistic combination. Vitamin D3 promotes calcium absorption, and MK-7 directs that calcium to bones rather than arteries. Together they support comprehensive bone and cardiovascular health.
Q10: What is the significance of "all-trans" MK-7?
A: The "all-trans" configuration is the biologically active and natural form of MK-7. It is the form found in nature and the form that binds effectively to the target proteins (osteocalcin and MGP). Other isomeric forms (cis-isomers) have lower biological activity.
Q11: Can MK-7 be used in cosmetics?
A: Yes - MK-7 is used as a skin protectant and antioxidant in various cosmetic formulations. Maximum recommended use levels vary by product type (face cream, hand cream, body lotion).
Q12: Is MK-7 suitable for gummies?
A: MK-7 is fat-soluble and requires oil-based formulation. Gummies can be formulated with emulsified or microencapsulated MK-7. Our formulation team can advise on stability and formulation.

 

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