Description

L-Glutamine Powder

L-Glutamine is the most abundant free amino acid in the human body, constituting approximately 61% of the amino acid pool in skeletal muscle tissue. It is classified as a non-essential amino acid because the body can synthesize it endogenously. However, during periods of metabolic stress-intense training, illness, injury, or gastrointestinal disorders-the body's demand for glutamine often exceeds its capacity to produce it, making it "conditionally essential."

🛡️ The "Conditional Essential" for Immunity and Recovery: L-Glutamine serves two primary functions. First, it is a critical metabolic fuel - the major energy source for rapidly dividing cells such as enterocytes (intestinal lining cells) and lymphocytes (white blood cells), playing a vital role in maintaining gut barrier integrity and supporting immune function. Second, it is a key regulator of muscle protein synthesis, helping to prevent muscle breakdown during catabolic states and supporting recovery after exercise.

⚠️ Stability Note: As a dry powder, L-Glutamine is highly stable. However, it degrades rapidly in liquid media or solution, potentially producing toxic byproducts. For this reason, it is often recommended to mix glutamine powder into a beverage and consume it immediately, rather than storing it in a pre-mixed solution.

Specification: 98.5% – 101.5% (on dried basis)
Sample: Sample Available
Test method: HPLC / Titration (Perchloric acid) / USP method
Synonyms: L-Glutamine, Gln, Levoglutamide, (S)-2,5-Diamino-5-oxopentanoic acid, Glutamic acid amide
MOQ: 1 KG | Package: 1kg/foil bag, 25kgs/drum
Certificate: HACCP, ISO 22000, GMP, HALAL (available upon request), Kosher (available upon request)
Molecular Formula: C₅H₁₀N₂O₃ | CAS: 56-85-9

Product Characteristics

🧂

Appearance

White to almost white crystalline powder; odorless.

⚗️

Purity

98.5% – 101.5% (USP/EP grade available).

💧

Solubility

Soluble in water (~35–100 g/L at 20°C).

⚖️

pH (25 g/L solution)

4.0 – 6.0 - gentle on the stomach.

📏

Particle Size

>95% pass 80 mesh.

🏭

GMP Manufacturing

Advanced fermentation with full traceability.

COA (Certificate of Analysis)

Benefits of L-Glutamine Powder

01Gut Barrier Integrity & Digestive Health

Glutamine serves as the primary metabolic fuel for enterocytes (intestinal epithelial cells). Helps maintain intestinal lining integrity, supporting gut barrier function and preventing "leaky gut."

02Immune System Support

Lymphocytes and other immune cells are highly dependent on glutamine as an energy source. Adequate glutamine levels support immune cell proliferation and function, especially during times of physical stress.

03Muscle Recovery & Protein Synthesis

As a key regulator of muscle protein synthesis, glutamine supports recovery after exercise. Helps prevent muscle breakdown during catabolic states and promotes lean muscle preservation.

04Neurotransmitter Precursor

Glutamine is a precursor to the neurotransmitters glutamate and gamma-aminobutyric acid (GABA), playing a role in maintaining healthy brain function and stress response.

05Cell Culture & Research Applications

A crucial component of cell culture media, serving as a major energy source for propagating cells. Used in MEM, DMEM, and other culture media formulations.

06Conditionally Essential - Supports Stress States

During periods of high stress, intense training, illness, or gastrointestinal disease, the body's demand for glutamine exceeds production capacity - supplementation helps bridge the gap.

Application Fields

Dietary Supplements (Hero Application): Sports nutrition & recovery blends (5–20 g), gut health & digestive support formulas, post‑workout & muscle preservation blends (with BCAAs, creatine), capsules & tablets, powder blends & stick packs, gummies & chewables.
Clinical Nutrition & Medical Foods: Enteral nutrition formulas for catabolic conditions, recovery products for post‑surgical and post‑illness recovery.
Cell Culture & Biopharma: Cell culture media supplement (MEM, DMEM).
OEM Finished Products: Recovery powder sticks, glutamine capsules, post‑workout blends, recovery gummies, gut health formula - full custom manufacturing available.

Production Process

Production process of L-Glutamine

Process: Fermentation (non‑GMO microorganisms on plant‑based substrates) → ion‑exchange chromatography → activated carbon treatment → crystallization → gentle drying → milling → sieving → packaging.

Product Quality Advantage

98.5% – 101.5% Purity – USP/EP grade available.

Conditionally Essential – Supports stress states.

Low Heavy Metals – Pb <2 ppm.

Low Ammonium – ≤0.01%.

Excipient‑Free – 100% active ingredient.

cGMP Certified – Full traceability and documentation.

Annual Capacity: 1,500 Tons | 15+ years of amino acid expertise

Professional ODM/OEM Services

We provide full OEM/ODM manufacturing for finished products using L-Glutamine as the active ingredient - from concept to commercial delivery, all under one roof.

① Finished Dosage Forms
Capsules: 500 mg, 1000 mg; vegetarian/gelatin; custom bottle/blister.
Tablets: Direct compression; round/oval; debossing.
Chews & Gummies: Natural/artificial flavors; sugar‑free options.
Powder Blends: Stick packs, tubs; with BCAAs, creatine, collagen.
Liquids: For immediate consumption only (not for storage).
Bars: Protein bars, snack bars.

② Combination Options
L-Glutamine + BCAAs (recovery), L-Glutamine + Collagen (gut health), L-Glutamine + Creatine (muscle preservation).

③ Additional Services
Flavor development, third‑party certification (NSF, Informed Sport, Kosher, HALAL), stability testing, regulatory documentation.

📧 Email: wangjing@landnutra.com

📱 WhatsApp: +86 18092657549

All backed by LANDNUTRA's quality assurance - full GMP, Halal, Kosher, COA certification and complete traceability from sourcing to finished product.

Export Certificates

Certificates HACCP ISO GMP Halal Kosher

Why choose us

XI'AN LANDNUTRA CO., LTD. – Your Trusted Manufacturer of Functional Ingredients. Rooted in Quality, Driven by Expertise, Committed to Health and Excellence.

Strong Production Capability: Annual capacity 1,500 tons. 15+ years experience, own facility.
Leading Service: ONE-STOP OEM/ODM from pre-sales to after-sales.
Quality Assurance: CQC-certified enterprise, purity embedded in every process.
Broad Market: Botanical Extracts, Cosmetic Ingredients, Functional Ingredients.

15+ years of experience in functional ingredients and amino acid manufacturing. Vertically integrated from raw material sourcing to finished goods manufacturing. Batch‑specific COA including assay, optical rotation, heavy metals, ammonium, and microbiological limits. Technical support for formulation and stability.

FAQ

Q1: What is L-Glutamine and what does it do?

A: L-Glutamine is the most abundant free amino acid in the body. It serves as a key fuel source for immune cells and intestinal cells, supporting immune function and gut barrier integrity. It also plays a vital role in muscle recovery and protein synthesis.

Q2: What is the recommended daily dose?

A: Typical doses range from 5 g to 20 g per day, depending on individual needs and activity levels. For general recovery and immune support, 5–10 g per day is common. Always consult a healthcare provider for personalized recommendations.

Q3: Is L-Glutamine essential?

A: L-Glutamine is classified as a non-essential amino acid because the body can synthesize it. However, it becomes conditionally essential during periods of high stress, intense training, illness, or gastrointestinal disease, when demand exceeds production capacity.

Q4: Can I mix L-Glutamine in liquid and store it?

A: No. L-Glutamine degrades rapidly in aqueous solutions, potentially forming toxic byproducts. It should be mixed into a beverage and consumed immediately. Best suited for powder blends, capsules, and tablets.

Q5: Is L-Glutamine safe?

A: L-Glutamine is generally well-tolerated and has been used safely in clinical studies at doses up to 30 g/day. Some individuals may experience mild gastrointestinal discomfort at very high doses.

Q6: Is L-Glutamine vegan?

A: Yes. Our L-Glutamine is produced via fermentation from non-animal sources. It does not contain any animal-derived components.

Q7: What is the shelf life?

A: 24 months in original sealed container under cool, dry conditions (≤25°C, ≤60% RH). Once opened, use within 12 months and keep container tightly sealed.

Q8: Can L-Glutamine be used in cell culture?

A: Yes. L-Glutamine is a crucial component of cell culture media, serving as a major energy source for propagating cells. It is typically stored as a dry powder or frozen solution, and added to liquid media immediately before use.

Q9: Can L-Glutamine be combined with other supplements?

A: Yes. It is commonly combined with BCAAs, creatine, and collagen for synergistic recovery, muscle preservation, and gut health benefits.

Q10: Does L-Glutamine help with gut health?

A: Yes. Glutamine is the primary fuel source for intestinal epithelial cells (enterocytes), helping to maintain gut barrier integrity and support digestive health.

Q11: Is L-Glutamine stable in powder form?

A: Yes. As a dry powder, L-Glutamine is highly stable for 24+ months when stored under proper conditions (cool, dry, sealed).

Q12: Is L-Glutamine safe during pregnancy?

A: L-Glutamine is a naturally occurring amino acid, but high‑dose supplementation during pregnancy is not well studied. Always consult a healthcare provider before use.

Test Item	Specification (USP/EP Grade)	Test Result	Conclusion
Appearance	White to almost white crystalline powder	Conforms	Pass
Assay (Dried Basis)	98.5% – 101.5%	99.6%	Pass
Specific Optical Rotation	+31.5° to +33.0°	+32.3°	Pass
pH (25 g/L solution)	4.0 – 6.0	5.2	Pass
Loss on Drying	≤0.3%	0.2%	Pass
Heavy Metals (as Pb)	≤10 ppm	<2 ppm	Pass
Total Plate Count	≤1,000 cfu/g	<100 cfu/g	Pass
E. Coli / Salmonella	Negative	Negative	Pass

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