Description

Magnesium Acetate Tetrahydrate Powder

Magnesium Acetate Tetrahydrate is a hydrated, water‑soluble magnesium salt of acetic acid, commonly encountered in laboratory, pharmaceutical, and nutritional applications where a neutral to slightly alkaline magnesium source is required.

Chemical Identity: The tetrahydrate form contains four moles of water of crystallization per mole of magnesium acetate. This hydration state is the most commercially common form, as it is stable under normal storage conditions and provides predictable solubility characteristics.

Typical Use Contexts: Buffer preparation (particularly in combination with acetic acid for acetate buffer systems), reagent in organic synthesis (e.g., condensation reactions), drying agent or catalyst in certain chemical processes, and electrolyte source in specialized nutritional or clinical formulations.

Comparison with Other Magnesium Salts: Unlike magnesium oxide (poor solubility) or magnesium citrate (high solubility with organic anion), magnesium acetate offers complete solubility in water, a neutral to mildly alkaline pH in solution, and a relatively high magnesium content per gram (approximately 11.3% elemental Mg in the tetrahydrate form).

Regulatory and Quality Note: While magnesium acetate is not as widely used in dietary supplements as citrate or glycinate, it is recognized in pharmacopoeias (e.g., USP, EP) and is permitted as a nutrient or processing aid in certain food categories depending on regional regulations.

Specification: 98.0% – 102.0%
Sample: Sample Available
Test method: Titration / ICP-MS / USP method
Synonyms: Magnesium diacetate tetrahydrate, Acetic acid magnesium salt tetrahydrate
MOQ: 1 KG | Package: 1kg/foil bag, 25kgs/drum
Certificate: HACCP, ISO 22000, GMP (HALAL pending raw material verification)
Molecular Formula: Mg(CH₃COO)₂·4H₂O | CAS: 16674-78-5

Product Characteristics

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Appearance

White or colorless crystalline powder; slight acetic odor.

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Elemental Magnesium

Approximately 11.3% Mg by weight in tetrahydrate form.

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Solubility

Highly soluble in water (~56 g/100 mL at 20°C). Solutions are clear and colorless.

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pH of Aqueous Solutions

1% solution pH 7.0–8.5 (neutral to weakly alkaline).

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Particle Size

>95% pass 80 mesh (standard), custom available.

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GMP Manufacturing

Produced in certified facilities with batch‑to‑batch consistency.

COA (Certificate of Analysis)

Benefits of Magnesium Acetate Tetrahydrate Powder

01Magnesium Electrolyte Source

Essential for over 300 enzymatic reactions, including ATP metabolism, protein synthesis, muscle function, and nerve transmission.

02Buffer Capacity

When combined with acetic acid, forms an effective acetate buffer system (pKa ≈ 4.76) for biochemical and analytical applications.

03Lower Gastric Irritation (Relative to Chloride)

Less acidic than magnesium chloride, potentially offering improved gastric tolerance for oral applications.

04Solubility Advantage Over Oxide

Unlike magnesium oxide (poor solubility, variable bioavailability), magnesium acetate dissolves completely in water.

05Low Residual Acidity

Solutions are neutral to slightly alkaline - advantageous in formulations where low acidity is desired.

06Good Compatibility in Liquid Formulations

Complete solubility and neutral pH make it suitable for liquid nutritional products, oral solutions, and electrolyte formulas.

Application Fields

Laboratory & Analytical Reagent: Preparation of acetate buffer systems, reagent in organic synthesis, reference standard in analytical chemistry.
Pharmaceutical & Clinical Nutrition: Excipient in certain preparations, electrolyte source in specialized enteral/parenteral formulations, component in dialysis solutions.
Nutritional Supplements (Limited Use): Liquid magnesium supplements, electrolyte replacement powders, buffered magnesium formulations.
Food Additive / Processing Aid: Permitted as nutrient supplement or acidity regulator (EU E‑number E263). Regulatory status varies by country.
Cosmetic & Personal Care: Occasional use as viscosity control agent or buffering component.

Production Process

Production process of Magnesium Acetate Tetrahydrate

Product Quality Advantage

98%–102% Assay – High purity, consistent quality.

11.3% Elemental Mg – Efficient magnesium content.

Excellent Solubility – Complete dissolution in water.

Neutral to Alkaline pH – Gentle on formulations.

Full Traceability – Batch-specific COA and stability data.

cGMP Certified – Documented quality systems.

Annual Capacity: 1,500 Tons | 15+ years of ingredient production expertise

Professional ODM/OEM Services

We deliver end-to-end ODM/OEM solutions for Magnesium Acetate products. From concept to finished bottle - we've got you covered.

① Cooperation Models
OEM: Reproduce your formula with guaranteed consistency.
ODM: Complete formulation, development, and compliant manufacturing.

② Key Process
Analysis & Design: Custom solutions based on your needs.
Prototyping: Sample development using advanced tech.
Production: Certified manufacturing with rigorous QC.

Customizable finished products: Liquid magnesium drops, electrolyte blends (Mg + K + Ca), private label magnesium acetate powder, custom buffer preparations.

Export Certificates

Certificates HACCP ISO GMP

Why choose us

XI'AN LANDNUTRA CO., LTD. – Your Trusted Manufacturer of Antioxidant & Functional Ingredients. Rooted in Quality, Driven by Expertise, Committed to Health and Excellence.

Strong Production Capability: Annual capacity 1,500 tons. 15+ years experience, own facility.
Leading Service: ONE-STOP OEM/ODM from pre-sales to after-sales.
Quality Assurance: CQC-certified enterprise, purity embedded in every process.
Broad Market: Botanical Extracts, Cosmetic Ingredients, Functional Ingredients.

Fifteen years of manufacturing mineral salts and organic acid derivatives. cGMP‑certified facilities. Full lot traceability with batch‑specific COA, including heavy metals, water content, and microbiological data. The product is manufactured under documented quality systems that support regulatory inspection and customer auditing.

FAQ

Q1: What is the elemental magnesium content of Magnesium Acetate Tetrahydrate?

A: Approximately 11.3% Mg by weight. (Calculation: 24.3 g/mol Mg ÷ 214.4 g/mol compound ≈ 0.113.) Compare to magnesium citrate (~16% Mg), magnesium oxide (~60% Mg), and magnesium chloride (~12% Mg in hexahydrate form).

Q2: Why would one choose magnesium acetate over more common magnesium salts for supplementation?

A: For most oral supplement applications, magnesium citrate or bisglycinate are preferred due to better tolerability and established bioavailability data. Magnesium acetate is more likely to be used in liquid formulations, buffer systems, or research contexts where acetate is the desired counterion. It is less common as a first‑line dietary supplement ingredient.

Q3: Does magnesium acetate have an acetic (vinegar) odor?

A: Yes, a faint acetic odor may be present. This is intrinsic to the compound and does not indicate degradation or impurity. In finished products (capsules, tablets, flavored liquids), the odor is typically not noticeable.

Q4: Is magnesium acetate suitable for vegans?

A: Yes, provided the acetic acid source is synthetic (petrochemical or fermentation‑derived) rather than from animal‑derived vinegar. Our manufacturing process uses synthetic acetic acid. A vegan suitability statement is available upon request.

Q5: How should it be stored?

A: Store in a cool, dry location in tightly sealed containers. The tetrahydrate is moderately hygroscopic; excessive humidity may cause caking or surface dissolution. Do not store above 40°C for prolonged periods.

Q6: Can magnesium acetate be used in tablet compression?

A: It may be used as an active ingredient or excipient in tablets, but its hygroscopicity and potential for picking/sticking should be evaluated. Pre‑formulation studies (flow, compressibility, lubricant compatibility) are recommended. We offer technical support for formulation inquiries.

Q7: Is there a risk of acetates causing an acetic taste in finished products?

A: At typical dietary magnesium doses (e.g., 100–400 mg elemental magnesium), the amount of acetate ion is relatively small (~1–3 grams equivalent acetic acid). In most solid dosage forms, no taste is detectable. In liquid solutions without flavor masking, a slight vinegar‑like note may be noticed by sensitive individuals.

Q8: What is the difference between tetrahydrate and anhydrous magnesium acetate?

A: The tetrahydrate contains four water molecules per formula unit (water content ~33%). The anhydrous form has been dried to remove this water. Anhydrous is more hygroscopic and less common commercially. The tetrahydrate is the standard commercial form due to its better handling stability.

Q9: Is this product USP grade?

A: Magnesium Acetate Tetrahydrate is recognized in USP–NF (see monograph for Magnesium Acetate). We can supply material meeting USP specifications upon request. Please contact us for batch‑specific USP compliance status.

Q10: What is the shelf life?

A: 24 months from date of manufacture when stored under recommended conditions (cool, dry, sealed container). Stability data (including assay, water content, and appearance) are available upon request.

Test Item	Specification	Test Result	Conclusion
Appearance	White or colorless crystalline powder	Conforms	Pass
Assay (as Mg(CH₃COO)₂·4H₂O)	98.0% – 102.0%	99.4%	Pass
Magnesium Content (as Mg)	10.8% – 11.8%	11.4%	Pass
pH (5% solution)	7.0 – 8.5	7.6	Pass
Water Content (KF)	31.0% – 36.0%	33.5%	Pass
Chlorides (as Cl)	≤ 0.05%	<0.01%	Pass
Sulfates (as SO₄)	≤ 0.05%	<0.01%	Pass
Heavy Metals (as Pb)	≤ 10 ppm	<5 ppm	Pass
Arsenic (As)	≤ 3 ppm	<1 ppm	Pass
Total Plate Count	≤ 1,000 cfu/g	<100 cfu/g	Pass
Yeast & Mold	≤ 100 cfu/g	<10 cfu/g	Pass
E. Coli / Salmonella	Negative	Negative	Pass

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