Description

Nicotinamide Riboside Chloride Powder

Nicotinamide Riboside (NR) is a naturally occurring form of Vitamin B3, originally identified as a trace nutrient in milk. It has gained significant attention in the health and longevity space for its role as a highly efficient precursor to Nicotinamide Adenine Dinucleotide (NAD+) - a vital coenzyme found in every living cell.

⚡ The "NAD+ Booster" for Cellular Energy: Think of NAD+ as the fuel that powers your cellular engines. It is essential for energy production, DNA repair, and activating longevity proteins called sirtuins. Unfortunately, NAD+ levels decline naturally with age, a process linked to metabolic slowdown and age-related decline.

Nicotinamide Riboside offers a unique and efficient pathway to replenish NAD+. Unlike nicotinic acid, NR does not cause uncomfortable flushing. It works by entering cells and being converted to NAD+ through a salvage pathway, effectively "recharging" your cellular batteries.

Our Nicotinamide Riboside Chloride powder is the most common and widely studied salt form of NR, known for its stability and bioavailability. It is produced to meet strict quality specifications for use as a dietary supplement.

❄️ Storage Note: Nicotinamide Riboside Chloride is hygroscopic and sensitive to light and heat. Store in original sealed container under inert gas (nitrogen or argon) at 2-8°C. Our packaging is designed to protect the product to ensure a 24-month shelf life.

Specification: ≥90% (w/w, typical assay 97-99%)
Sample: Sample Available
Test method: HPLC-UV / NMR / Karl Fischer (USP <921>)
Synonyms: Nicotinamide riboside chloride, NR, Niagen®, Vitamin B3 derivative, NAD+ precursor
MOQ: 1 KG | Package: 1kg/foil bag (under inert gas recommended), 25kgs/drum
Certificate: HACCP, ISO 22000, GMP, Novel Food compliant (EU 2020/16, Australia/New Zealand)
Molecular Formula: C₁₁H₁₅ClN₂O₅ | CAS: 23111-00-4

Product Characteristics

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Appearance

White to off-white powder.

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Purity

≥90% (w/w), typical 97-99% - high potency.

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Solubility

Freely soluble in water (10 mg/mL) - ideal for formulations.

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NAD+ Precursor

Increases intracellular and mitochondrial NAD+ content.

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Particle Size

>95% pass 80 mesh.

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GMP Manufacturing

Produced in certified facilities with strict quality control.

COA (Certificate of Analysis)

Benefits of Nicotinamide Riboside Chloride Powder

01Boosts NAD+ Levels

NR is a highly efficient NAD+ precursor, bypassing rate‑limiting steps in the salvage pathway. Studies show NR can increase NAD+ by up to 60%, recharging cellular batteries.

02Supports Cellular Energy & Metabolism

NAD+ is essential for converting food into energy. Increased NAD+ supports healthy mitochondrial function, improves oxidative metabolism, and protects against metabolic abnormalities.

03Promotes Healthy Aging

NAD+ is a substrate for sirtuins - proteins linked to longevity and stress resistance. By boosting NAD+, NR supports cellular repair, DNA integrity, and healthy aging.

04Neuroprotective Effects

Research suggests NR may reduce hippocampal damage and preserve cognitive function, indicating potential for brain health support.

05No Flushing - Unlike Niacin

Unlike nicotinic acid, NR does not cause uncomfortable vasodilation (flushing), making it a more comfortable choice for daily supplementation.

06Novel Food Compliant & Regulatory Ready

Authorized as a Novel Food in the EU (Regulation 2020/16) and approved in Australia/New Zealand. Fully compliant with strict global specifications.

Application Fields

Dietary Supplements (Hero Application): Capsules & tablets (250–600 mg), powder blends & stick packs, gummies & chews, multivitamin blends.
Functional Foods & Beverages: Energy drinks & shots, protein powders & meal replacements.
Cosmetics (Emerging): Skin serums & creams (NAD+ anti‑aging benefits).
OEM Finished Products: NR capsules, anti‑aging powder sticks, energy gummies, cellular support softgels, custom NAD+ precursor blends - full custom manufacturing available.

Production Process

Production process of Nicotinamide Riboside

Process: Synthetic route combining nicotinamide with ribose derivative → multiple purification steps → crystallization → controlled drying → milling → sieving → inert gas packaging.

Product Quality Advantage

≥90% Purity – Typical 97-99%, high potency.

Novel Food Compliant – EU 2020/16, FSANZ approved.

Low Heavy Metals – Pb <0.1 mg/kg, As <0.2 mg/kg.

Low Acetamide – <5 mg/kg (strict quality control).

Inert Gas Packaging – Ensures 24-month stability.

cGMP Certified – Full traceability and documentation.

Annual Capacity: 1,500 Tons | 15+ years of ingredient expertise

Professional ODM/OEM Services

We provide full OEM/ODM manufacturing for finished products using Nicotinamide Riboside Chloride as the active ingredient - from concept to commercial delivery, all under one roof.

① Finished Dosage Forms
Capsules: 250 mg, 300 mg, 500 mg; vegetarian/gelatin; custom bottle/blister.
Tablets: Direct compression; round/oval; debossing.
Chews & Gummies: Custom flavors, sugar‑free options.
Powder Blends: Stick packs, tubs; with pterostilbene, resveratrol, CoQ10.
Liquids: Suspensions, RTD beverages.
Bars: Protein bars, snack bars.

② Combination Options
NR + Pterostilbene (anti‑aging), NR + Resveratrol (sirtuin activation), NR + CoQ10 (cellular energy).

③ Additional Services
Flavor development, third‑party certification (NSF, Informed Sport, Kosher, HALAL), stability testing (real‑time and accelerated), regulatory documentation (EU Novel Food, FSANZ compliance support).

📧 Email: wangjing@landnutra.com

📱 WhatsApp: +86 18092657549

All backed by LANDNUTRA's quality assurance - full GMP, Halal, Kosher, COA certification and complete traceability from sourcing to finished product.

Export Certificates

Certificates HACCP ISO GMP

Why choose us

XI'AN LANDNUTRA CO., LTD. – Your Trusted Manufacturer of Functional Ingredients. Rooted in Quality, Driven by Expertise, Committed to Health and Excellence.

Strong Production Capability: Annual capacity 1,500 tons. 15+ years experience, own facility.
Leading Service: ONE-STOP OEM/ODM from pre-sales to after-sales.
Quality Assurance: CQC-certified enterprise, purity embedded in every process.
Broad Market: Botanical Extracts, Cosmetic Ingredients, Functional Ingredients.

15+ years of experience in functional ingredients. Vertically integrated from raw material sourcing to finished goods manufacturing. Expertise in handling sensitive bio‑actives. Batch‑specific COA including full specification testing per EU 2020/16 and FSANZ A1214 standards. Technical support for formulation and stability.

FAQ

Q1: What is the difference between Nicotinamide Riboside (NR) and NMN?

A: Both are NAD+ precursors. NR is slightly smaller and may be more efficient at entering cells. NMN is one step closer to NAD+ but requires conversion to NR before entering cells in some tissues. NR is currently the more studied and widely adopted commercial form for NAD+ boosting.

Q2: What is the recommended dosage?

A: Typical supplemental doses range from 250 mg to 600 mg per day. As per EFSA, Nicotinamide Riboside Chloride is safe for use in food supplements at levels established in the Novel Food regulation.

Q3: Is Nicotinamide Riboside a drug or a supplement?

A: In major markets (US, EU, Australia), NR is authorized as a food ingredient or supplement ingredient. In the EU, NR chloride is authorized as a Novel Food under Regulation (EU) 2020/16.

Q4: Does Nicotinamide Riboside cause flushing like Niacin?

A: No. Unlike nicotinic acid, NR does not cause the uncomfortable vasodilation (flushing) associated with niacin.

Q5: Why is it called a "chloride" salt?

A: The chloride salt form is the most common and stable form of NR used in supplements and research. It combines nicotinamide riboside with chloride to improve stability and bioavailability.

Q6: How should I store Nicotinamide Riboside powder?

A: Store in the original sealed container, protected from light, under inert gas (nitrogen or argon), at 2-8°C. It is hygroscopic and sensitive to moisture.

Q7: Is Nicotinamide Riboside natural?

A: It is synthesized, not extracted, but it is "nature-identical" and found in trace amounts in foods like milk.

Q8: Can I take Nicotinamide Riboside every day?

A: Yes, it is designed for daily use as a dietary supplement to support healthy NAD+ levels.

Q9: Is Nicotinamide Riboside safe?

A: Yes. Extensive safety studies have shown NR has a good safety profile. In a 90‑day toxicology study, the NOAEL was established at 300 mg/kg/day.

Q10: Is Nicotinamide Riboside vegan?

A: Yes - our NR is produced via synthesis with no animal‑derived materials. Suitable for vegan and vegetarian products.

Q11: Can Nicotinamide Riboside be used in beverages?

A: Yes - it is freely soluble in water (10 mg/mL), making it suitable for RTD beverages, energy shots, and functional drinks.

Q12: What is the shelf life of Nicotinamide Riboside powder?

A: 24 months in original sealed container under inert gas, stored at 2-8°C, protected from light and moisture.

Test Item	Specification (EU Novel Food & USP Grade)	Test Result	Conclusion
Appearance	White to off-white powder	Conforms	Pass
Assay (HPLC)	≥90.0%	98.5%	Pass
Water Content (KF)	≤2.0%	0.5%	Pass
Lead (Pb)	≤0.5 mg/kg	<0.1 mg/kg	Pass
Arsenic (As)	≤1.0 mg/kg	<0.2 mg/kg	Pass
Acetamide	≤27 mg/kg	<5 mg/kg	Pass
Total Plate Count	≤1,000 CFU/g	<100 CFU/g	Pass
E. Coli / Salmonella	Absent/10g	Negative	Pass

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