Description

1,4-Dipropionato Benzene Powder

Let's talk about a molecule that most people have never heard of - but your liquid crystal display (LCD) knows it intimately.

1,4-Dipropionato Benzene (abbreviated as 1,4-DPB for those of us who value our vocal cords) is not a flashy compound. It doesn't smell like citrus. It doesn't make your skin glow. What it does is much more subtle, but absolutely essential: it builds bridges.

The Chemistry of Order: At its core, 1,4-DPB consists of a central benzene ring with two propionate ester groups attached at the para (1,4) positions. This structure is linear, symmetrical, and rigid - a tiny, perfect rod. Molecules like this are the building blocks of liquid crystals.

When you melt 1,4-DPB and cool it under specific conditions, the molecules align - like a field of wheat all bending the same direction. That aligned phase (the nematic or smectic liquid crystal phase) is what allows an LCD screen to twist light, create contrast, and display a sharp image.

Other Identities: You may also encounter this molecule under the name hydroquinone dipropionate. Yes - it's hydroquinone with two propionic acid groups attached. The esterification makes it much less polar, more lipophilic, and completely changes its physical properties.

⚠️ Important Notice: 1,4-Dipropionato benzene is a laboratory chemical and research intermediate. It is NOT a cosmetic ingredient. Do not formulate into leave‑on skin products. The ester groups can hydrolyze to release hydroquinone, which is banned in cosmetics in many countries (EU, UK, Japan).

Specification: 98.0% – 102.0% (on dried basis)
Sample: Sample Available
Test method: HPLC / GC / DSC (melting point)
Synonyms: Hydroquinone dipropionate, 1,4-Benzenediol dipropionate, Hydroquinone dipropanoate
MOQ: 1 KG | Package: 1kg/foil bag (double-sealed, moisture-proof), 25kgs/fiber drum
Certificate: HACCP, ISO 22000, GMP (HALAL status varies by batch; contact for details)
Molecular Formula: C₁₂H₁₄O₄ | CAS: 7400-28-4

Product Characteristics

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Appearance

Fine, free‑flowing white to off-white crystalline powder; faint characteristic odor.

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Molecular Weight

222.24 g/mol - rigid, rod‑shaped structure ideal for liquid crystal research.

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Melting Point

118 – 122°C (sharp melt; range ≤2°C indicates high purity).

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Solubility

Insoluble in water. Soluble in ethanol, acetone, ethyl acetate, THF, and toluene.

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Particle Size

>95% pass 80 mesh; micronized available.

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GMP Manufacturing

Esterification of hydroquinone with propionic acid; purified by recrystallization.

COA (Certificate of Analysis) – High‑Purity Grade

Benefits of 1,4-Dipropionato Benzene

01Model Smectogen for Liquid Crystal Research

1,4-DPB is a classic compound used to study smectic liquid crystal phases. Its simple, rigid rod‑like structure allows researchers to investigate molecular packing without complications of complex fluorinated mesogens.

02Polarized Light Microscopy Standard

Forms clear, well‑defined textures (e.g., focal conic fans in the smectic A phase). Used as a teaching and calibration standard in liquid crystal laboratories worldwide.

03Versatile Intermediate for Organic Synthesis

The two ester groups can be further reacted via transesterification, amidation, or reduction. A versatile building block for polymers, liquid crystal dimers, and specialty chemicals.

04Protecting Group Strategy

Esterification protects the hydroquinone core during multi‑step syntheses. Propionate groups can be cleaved under mild basic conditions to regenerate hydroquinone when needed.

05Monomer for Polyester Synthesis

Can be reacted with diols via transesterification to produce aromatic‑aliphatic polyesters with potential biodegradability and liquid crystal properties.

06High Purity & Sharp Melting Point

≥99.5% purity with melting point 120 ± 2°C ensures consistent crystalline form - critical for reproducible research and synthesis.

Application Fields

Research & Development (Academic & Industrial Labs): Liquid crystal phase studies (DSC, polarized light microscopy, X‑ray diffraction), synthesis of liquid crystal dimers & trimers, polymer synthesis (polyester precursor), model compound for ester hydrolysis kinetics.
Industrial Intermediates: Production of hydroquinone derivatives, specialty coating additives (crystalline additive for texture control).
Custom Manufacturing: Bulk synthesis, custom particle size, custom purity grades (99.9% available on request), custom liquid crystal blends, pre‑weighed synthesis kits for academic labs.

Production Process

Production process of 1,4-Dipropionato Benzene

Product Quality Advantage

≥98% Purity (≥99.5% HP grade) – High‑purity crystalline powder.

Low Free Hydroquinone – ≤0.02% (minimizes toxicity concerns).

Low Free Propionic Acid – ≤0.05% (reduces odor and corrosion).

Sharp Melting Point – 120 ± 2°C (consistent crystalline form).

Rigid Rod‑Shaped Molecule – Ideal for liquid crystal studies.

cGMP Certified – Full traceability and documentation.

Annual Capacity: 1,500 Tons | 15+ years of organic synthesis expertise

Professional ODM/OEM Services

We provide custom manufacturing for research and industrial clients using 1,4-Dipropionato Benzene.

① Custom Manufacturing
Bulk Synthesis: Kg to ton scale.
Purification Services: Recrystallization, sublimation, column chromatography.
Custom Particle Size: For solid‑state reactions.
Custom Purity Grades: 99.9% available by special request.
Custom Liquid Crystal Blends: 1,4-DPB mixed with other mesogens (contact for feasibility).
Pre‑Weighed Synthesis Kits: For academic labs (1,4-DPB + catalysts + solvents).

② Analytical Support
HPLC, GC, DSC, TGA, FTIR, polarizing microscopy, stability studies (hydrolysis kinetics).

③ Regulatory Documentation
REACH, TSCA, export certificates, MSDS, COA per batch.

Export Certificates

Certificates HACCP ISO GMP

Why choose us

XI'AN LANDNUTRA CO., LTD. – Your Trusted Manufacturer of Specialty Chemicals & Functional Ingredients. Rooted in Quality, Driven by Expertise, Committed to Excellence.

Strong Production Capability: Annual capacity 1,500 tons. 15+ years experience, own facility.
Leading Service: ONE-STOP OEM/ODM from pre-sales to after-sales.
Quality Assurance: CQC-certified enterprise, purity embedded in every process.
Broad Market: Botanical Extracts, Cosmetic Ingredients, Functional Ingredients, Specialty Chemicals.

15+ years of organic synthesis and specialty chemical manufacturing. cGMP‑certified facilities. Full in‑house analytical capabilities (HPLC, GC, DSC, FTIR, polarizing microscopy). Export documentation for research and industrial markets. Batch‑specific COA including melting point, assay, free hydroquinone, free propionic acid, and heavy metals. Technical support for liquid crystal formulation and synthesis applications.

FAQ

Q1: What is 1,4-dipropionato benzene used for?

A: Primarily for liquid crystal research (as a model smectogen) and as an intermediate in organic synthesis. It is a rigid, rod‑shaped molecule that aligns in the melt, making it useful for studying molecular ordering. It is not a common ingredient in commercial consumer products.

Q2: Is this the same as hydroquinone?

A: No. Hydroquinone is 1,4‑dihydroxybenzene (two free -OH groups). 1,4-Dipropionato benzene is hydroquinone with both -OH groups esterified with propionic acid. The ester groups block the free phenolic -OH, making this molecule non‑toxic compared to hydroquinone. It is not a skin lightener; it is a laboratory chemical.

Q3: Does this molecule have any cosmetic applications?

A: No - not directly. The ester could be hydrolyzed on skin (slowly) to release hydroquinone, which is banned in cosmetics in many countries. Do not formulate this into leave‑on skin products.

Q4: Is 1,4-DPB a liquid crystal?

A: It is a liquid crystal‑forming compound. Pure 1,4-DPB melts at 118–122°C to an isotropic liquid. Upon cooling, it may form a smectic liquid crystal phase before crystallizing. It is studied as a model compound, not a commercial LCD material.

Q5: Why is it called "dipropionato benzene" instead of "hydroquinone dipropionate"?

A: "Dipropionato benzene" is a systematic naming (benzene ring with two propionate substituents). "Hydroquinone dipropionate" names it as a derivative of hydroquinone. Both are correct; the former is more precise for chemical indexing.

Q6: Is this compound stable in water?

A: No. The ester bonds hydrolyze in water, especially at elevated temperatures or in the presence of acids or bases. The hydrolysis products are hydroquinone and propionic acid. If you need a water‑stable analogue, consider a di‑ether or a fluorinated derivative.

Q7: What is the shelf life of this powder?

A: 24 months in original sealed container under cool, dry conditions (≤25°C, ≤60% RH). Once opened, protect from moisture and use within 12 months.

Q8: Is 1,4-DPB toxic?

A: Acute toxicity is low. However, it is an ester of hydroquinone. If ingested, it may hydrolyze to hydroquinone in the stomach, which has moderate toxicity. Handle with standard laboratory precautions: gloves, safety glasses, fume hood. Do not taste, do not inhale dust.

Q9: Can I use 1,4-DPB to make hydroquinone?

A: Yes - hydrolyze it with dilute base (e.g., 1M NaOH, 60°C, 2 hours) to generate hydroquinone and sodium propionate. But hydroquinone is cheaper and easier to buy directly. This is a backwards route.

Q10: What is the difference between 1,4-dipropionato benzene and 1,4-diacetoxybenzene?

A: The ester group. Propionate has three carbons (−CO‑CH₂‑CH₃); acetate has two carbons (−CO‑CH₃). Propionate esters have slightly longer alkyl chains, which can affect liquid crystal phase behavior - they tend to promote smectic phases more than acetates.

Q11: Can this compound be used to make polymers?

A: Yes. It can be reacted with diols via transesterification to form polyesters. The resulting polymer would have hydroquinone in the backbone (a rigid aromatic unit) and propionate‑derived flexible spacers.

Q12: Why does the powder sometimes have a faint sweet smell?

A: That's the propionate ester group. Esters of short‑chain fatty acids often have sweet, fruity, or rum‑like odors. The odor does not indicate impurity or degradation; it's just the molecule being itself.

Test Item	Specification (High‑Purity Grade)	Test Result	Conclusion
Appearance	White to off-white crystalline powder	Conforms	Pass
Assay (HPLC)	98.0% – 102.0%	99.4%	Pass
Melting Point	118 – 122°C	120.3°C	Pass
Water Content (KF)	≤0.5%	0.1%	Pass
Free Hydroquinone	≤0.1%	0.02%	Pass
Free Propionic Acid	≤0.2%	0.05%	Pass
Lead (Pb)	≤1.0 ppm	<0.3 ppm	Pass
Total Plate Count	≤1,000 cfu/g	<100 cfu/g	Pass
E. Coli / Salmonella	Negative	Negative	Pass

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