Product Description
Nonapeptide-1 powder, a highly specific synthetic brightening peptide, regulates melanogenesis at upstream cellular signaling levels, it acts as a strong competitive antagonist for Melanocortin 1 Receptor (MC1R), blocks α-MSH attachment to melanocytes and suppresses all downstream melanin production chains, delivering dual pigment prevention and spot-lightening benefits unlike traditional tyrosinase-restricting brightening raw materials.
Compared with most mainstream lightening actives that work on later melanin formation stages, Nonapeptide-1 cuts off pigment-stimulating signals from the source, it efficiently relieves hyperpigmentation caused by UV exposure and skin inflammation, the peptide adopts D-amino acid modification and C-terminal amidation structures, offering strong resistance against skin protease degradation, steady bioavailability and minimal skin irritation with no cytotoxic impacts on melanocytes, it fits skincare formulas designed for sensitive and acne-prone complexions.
Our Nonapeptide-1 powder is produced through advanced solid-phase peptide synthesis and high-precision purification, it boasts consistent quality across batches and full biological activity, it acts as a high-grade mild lightening active for cosmetic formulas that even out skin tone and fade pigment spots.

Types of Peptide Products
Standard Cosmetic Grade (Purity 95–97%)
For daily brightening creams, lotions, and masks.
High-Purity Grade (Purity ≥98%)
For serums, ampoules, and professional skincare products.
Enhanced Stability Grade
Optimized for complex formulations and extended shelf life.
Nonapeptide-1 Powder Characteristics
Purity: ≥95%, fully synthetic, non-animal origin
Appearance: Fine white lyophilized powder
Solubility: Freely soluble in water and aqueous systems
pH Stability: Stable in pH range 4.5–7.0
Thermal Sensitivity: Heat-sensitive; add below 40°C
Storage: Store at 2–8°C for long-term stability, protected from light
COA (Certificate of Analysis)
|
Parameter |
Specification |
Test Method |
|
Appearance |
White powder |
Visual |
|
Purity |
≥95% |
HPLC |
|
Moisture |
≤6% |
Karl Fischer |
|
Peptide Identity |
Conforms |
MS |
|
Heavy Metals |
≤20 mg/kg |
ICP-MS |
|
Total Plate Count |
≤1000 CFU/g |
GB 4789.2 |

Processing Technology
High-purity Nonapeptide-1 powder is synthesized via solid-phase peptide chemistry and refined through multi-stage chromatography (ion exchange + RP-HPLC), with mass spectrometry and HPLC verification at every production stage.This stringent quality regime guarantees batch-to-batch consistency, exceptional purity, and stable bioactivity for premium cosmetic formulations.

Product Benefits
Blocks Melanin Generation at Source
By competitively blocking MC1R signal transmission, Nonapeptide-1 powder halts melanin synthesis at the upstream stage, outperforming common brightening raw materials that merely restrain pigment transfer.
01
Delivers Noticeable Brightening & Balanced Complexion
Consistent addition in formulations relieves hyperpigmentation and fades dark spots, evens dull mottled skin tone and generates stable visible lightening effects for all brightening skincare lines.
02
Mild Low-Irritation Alternative Brightening Active
Compared with hydroquinone and harsh acidic lightening ingredients, Nonapeptide-1 powder carries no cytotoxicity with mild skin-compatible action, serving as a safe compliant premium option for sensitive-skin formula development.
03
High Formulation Compatibility
Exhibits excellent compatibility with niacinamide, vitamin C derivatives, arbutin, and other bioactive peptides, adapting well to various formulation systems.
04
Ideal for Sensitive Skin Product Lines
Delivers high purity and precise MC1 receptor-targeting mechanism, offering a mild and non-irritating profile-particularly suitable for sensitive skin care and post-procedure repair product development.
05
Applications
Brightening Skincare:
Serums, essences, whitening creams, tone-up products
Professional Use:
Medical aesthetic products, post-laser or post-peel care
Advanced Formulations:
Anti-aging + brightening peptide complexes

Xi'an Land Nutra Company is certified official nonapeptide-1 powder manufacturers, premium nonapeptide-1 for sale available in stock;We maintain steady inventory and full after-sales service to be your trusted cosmetic raw material partner.Xi'an Land Nutra Company is Nonapeptide-1 wholesale premium wholesaler, if you are interested in our products, you can contact us.
Email: wangjing@landnutra.com
WhatsApp: +86 18092657549
Other Customizable Products (OEM / ODM)
We provide full customization support for:
1.Nonapeptide-1 Brightening Ampoules
2.Whitening & Spot-Correcting Serums
3.Peptide Complexes (Brightening + Anti-Aging)
4.Private Label Finished Products
Why Choose Our Nonapeptide-1?
Company Advantages
Dedicated peptide R&D and scale-up production capability
Strict QC system from synthesis to final release
Stable supply for long-term brand cooperation
Regulatory documentation support for global markets
Product Advantages
High activity with proven melanogenesis inhibition mechanism
Excellent formulation compatibility
Reliable batch consistency
Competitive pricing for bulk and long-term orders


FAQ
Q: Can you provide complete test documents for bulk orders?
A: We supply full COA, MSDS, heavy metal & microbial test reports, and cosmetic safety evaluation data upon request.
Q: What is the purity of your Nonapeptide-1 powder?
A:Our Nonapeptide-1 reaches ≥98% HPLC purity, white fine powder, stable for cosmetic formula preparation.
Q: Can it be used in daytime products?
A: Yes. Nonapeptide-1 is non-photosensitizing and suitable for day and night formulations.
Q: Is it compatible with vitamin C?
A: Yes, it shows good compatibility with stabilized vitamin C derivatives.
Q: Do you provide efficacy or stability data?
A: Yes, in-vitro activity data and accelerated stability reports are available upon request.
Q: What is your shipment method?
A: For large quantity of product orders, we usually ship the goods by sea.
For small quantity of product orders, we choose air or courier for shipment.
Depends on your preferences, we can deliver via many express companies such as DHL, FEDEX, UPS, TNT, etc.
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