Pomegranate Punicalagins Powder

Pomegranate Punicalagins Powder

Pomegranate Punicalagins Powder
1. Specification: 30% – 98% (HPLC, standardized extract or high-purity compound)
2. Sample: Sample Available
3. Test method: HPLC / UV-Vis
4. Synonyms: Punicalagin, Pomegranate ellagitannins, Pomegranate polyphenols, Pomegranate husk extract
5. Appearance: Fine, free‑flowing red-brown to light brown powder
6. Particle size: >95% pass 80 mesh
7. MOQ: 1 KG
8. Package: 1kg/foil bag, 25kgs/drum
9. Certificate: HACCP, ISO 22000, HALAL, GMP
10. Molecular Formula: C₄₈H₂₈O₃₀
11. Molecular Weight: 1084.72 g/mol
12. CAS number: 65995-63-3
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Description

 

Pomegranate Punicalagins Powder

Punicalagin is the primary ellagitannin and the most abundant polyphenol found in pomegranates (Punica granatum L.), accounting for more than 50% of the fruit's potent antioxidant activity. It is predominantly concentrated in the pomegranate husk (peel), which contains significantly higher levels than the arils or juice.

🧬 The "Powerhouse Polyphenol" from Pomegranate: While punicalagin itself is not directly absorbed into the bloodstream, its health benefits are profound. Once ingested, it is hydrolyzed by human gut microflora into ellagic acid, which is further metabolized into the highly bioavailable urolithins (particularly urolithin A). This unique pathway makes punicalagin a "prebiotic-like" polyphenol that exerts systemic effects through its metabolites.

Antioxidant Capacity: Punicalagin exhibits exceptionally high antioxidant activity. In ORAC (Oxygen Radical Absorbance Capacity) assays, it demonstrates values of 1556 ± 79 µmol of TE/g, significantly higher than many other known antioxidants. It effectively scavenges DPPH, ABTS, and hydrogen peroxide radicals.

❄️ Storage Note: Punicalagins are hygroscopic and sensitive to light. Store at 2–8°C (refrigerated) in the original sealed container, protected from light. For long-term storage, -20°C is recommended.

Specification: 30% – 98% (HPLC, standardized extract or high-purity compound)
Sample: Sample Available
Test method: HPLC / UV-Vis
Synonyms: Punicalagin, Pomegranate ellagitannins, Pomegranate polyphenols, Pomegranate husk extract
MOQ: 1 KG  |  Package: 1kg/foil bag, 25kgs/drum
Certificate: HACCP, ISO 22000, HALAL, GMP
Molecular Formula: C₄₈H₂₈O₃₀  |  Molecular Weight: 1084.72 g/mol  |  CAS: 65995-63-3

Pomegranate Punicalagins Powder
Product Characteristics
 
🧂

Appearance

Red-brown to light brown powder (extract) or faintly yellow to dark yellow (high-purity).
⚗️

Purity Range

30% – 98% (standardized extract or high-purity compound).
💧

Solubility

Soluble in methanol, DMSO, ethanol; sparingly soluble in water.
🧬

Mechanism

Gut microbiome conversion → ellagic acid → urolithins (systemic effects).
📏

Particle Size

>95% pass 80 mesh.
🏭

GMP Manufacturing

Botanical extraction with full traceability.

COA (Certificate of Analysis)

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Benefits of Pomegranate Punicalagins Powder

01Potent Antioxidant Activity

Punicalagin is a powerful free radical scavenger. ORAC values of 1556 ± 79 µmol TE/g - significantly higher than many other antioxidants. Protects cells from oxidative stress and DNA damage.

02Neuroprotection & Cognitive Support

Preclinical studies indicate punicalagin may help mitigate mild cognitive impairment (MCI) through antioxidative damage, anti-neuroinflammation, and promotion of neurogenesis.

03Cardiovascular Support

Improves lipid profiles and inhibits angiotensin-converting enzyme (ACE) activity, supporting cardiovascular health and healthy blood pressure.

04Anti-Inflammatory Modulation

Exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway, reducing the production of inflammatory cytokines.

05Gut Microbiome & Urolithin Production

Converted by gut microbiota into urolithins (including urolithin A) - linked to muscle health, mitochondrial function, and anti-aging benefits.

06Multiple Grades Available

Available as standardized extract (30–40%) or high-purity (≥90%–≥98%) to suit various applications - from dietary supplements to research and premium nutraceuticals.

Application Fields

Dietary Supplements (Hero Application): Capsules & tablets (antioxidant support, cardiovascular health, cognitive support), powder blends & stick packs, gummies & chewables, anti‑aging & healthy aging formulations.
Functional Foods & Beverages: Juice fortification, energy drinks & shots, protein powders.
Cosmetics & Personal Care: Anti‑aging skincare (serums, creams, masks).
Research & Analytical Standards: High‑purity grade (≥98%) for metabolomics and nutraceutical research.
OEM Finished Products: Antioxidant capsules, pomegranate polyphenol powder sticks, anti‑aging formula, brain health gummies, skin serum - full custom manufacturing available.

Production Process

Production process of Punicalagin

Process: Pomegranate peels → aqueous/hydro‑alcoholic extraction → column chromatography purification → vacuum concentration → spray/freeze drying → standardization → milling → sieving → light‑protected packaging.

Product Quality Advantage

30% – 98% Purity Range – Multiple grades for formulation flexibility.

High Antioxidant Activity – ORAC 1556 ± 79 µmol TE/g.

Low Heavy Metals – Pb <0.3 ppm, As <0.5 ppm.

Gut Microbiome Activation – Converts to bioavailable urolithins.

Botanical Source – Pomegranate peels, vegan.

cGMP Certified – Full traceability and documentation.

Extraction Facility
Quality Control Lab

Annual Capacity: 1,500 Tons | 15+ years of botanical extract expertise

Professional ODM/OEM Services

We provide full OEM/ODM manufacturing for finished products using Pomegranate Punicalagins as the active ingredient - from concept to commercial delivery, all under one roof.

① Finished Dosage Forms
Capsules: 100 mg, 250 mg, 500 mg; vegetarian/gelatin; custom bottle/blister.
Tablets: Direct compression; round/oval; debossing.
Chews & Gummies: Custom flavors, sugar‑free options.
Powder Blends: Stick packs, tubs; with resveratrol, urolithin precursors, CoQ10.
Cosmetics: Serums, creams, masks.
Bars: Protein bars, snack bars.

② Combination Options
Punicalagin + Resveratrol (anti-aging), Punicalagin + Urolithin A (longevity), Punicalagin + CoQ10 (cardiovascular).

③ Additional Services
Flavor development, third‑party certification (NSF, Kosher, HALAL), stability testing (2–8°C validation), regulatory documentation.

📧 Email: wangjing@landnutra.com

📱 WhatsApp: +86 18092657549

All backed by LANDNUTRA's quality assurance - full GMP, Halal, Kosher, COA certification and complete traceability from sourcing to finished product.

Export Certificates

Certificates HACCP ISO HALAL GMP

Why choose us

XI'AN LANDNUTRA CO., LTD. – Your Trusted Manufacturer of Functional Ingredients. Rooted in Quality, Driven by Expertise, Committed to Health and Excellence.

Strong Production Capability: Annual capacity 1,500 tons. 15+ years experience, own facility.
Leading Service: ONE-STOP OEM/ODM from pre-sales to after-sales.
Quality Assurance: CQC-certified enterprise, purity embedded in every process.
Broad Market: Botanical Extracts, Cosmetic Ingredients, Functional Ingredients.

15+ years of expertise in botanical extracts and polyphenol chemistry. Vertically integrated from raw material sourcing to finished goods manufacturing. Batch‑specific COA including assay, water content, heavy metals, and microbial limits. Technical support for formulation and stability.

FAQ

Q1: What is punicalagin, and where does it come from?
A: Punicalagin is the primary ellagitannin and the most abundant polyphenol found in pomegranates (Punica granatum L.). It is predominantly concentrated in the pomegranate husk (peel) and is responsible for over 50% of the fruit's antioxidant activity.
Q2: What is the difference between 30% extract and ≥98% punicalagin?
A: The 30% extract is a standardized pomegranate peel extract containing punicalagin as a key component, along with other polyphenols. It is cost-effective and suitable for most dietary supplement applications. The ≥98% grade is a highly purified compound for research, premium nutraceuticals, and pharmaceutical applications where high purity is essential.
Q3: Is punicalagin absorbed directly by the body?
A: No. Punicalagin is a large molecule that cannot be absorbed directly in the gastrointestinal tract. Instead, it is hydrolyzed by gut microflora into ellagic acid, which is further metabolized into urolithins (such as urolithin A), the bioavailable metabolites that exert systemic effects.
Q4: What are the health benefits of punicalagin?
A: Punicalagin exhibits potent antioxidant, anti-inflammatory, neuroprotective, and antimicrobial activities. It supports cardiovascular health, cognitive function, and may have anticancer potential. Its metabolites (urolithins) are linked to mitochondrial health and muscle function.
Q5: How should I store pomegranate punicalagins powder?
A: Store in the original sealed container, protected from light, at 2–8°C (refrigerated). For long-term storage, -20°C is recommended. It is hygroscopic, so ensure containers are tightly sealed after each use.
Q6: Is pomegranate punicalagins powder vegan?
A: Yes. Our product is derived from pomegranate peels (botanical origin). It does not contain any animal-derived components.
Q7: What is the shelf life?
A: ≥12 months when stored properly at -20°C in the original sealed container. For 30% extract grades, consult batch-specific stability data.
Q8: Is punicalagin safe for human consumption?
A: Punicalagin-rich pomegranate extracts have been shown to be safe. A study involving 86 overweight human individuals reported no adverse effects after administering 1420 mg/day of pomegranate fruit extract for 28 days. Consult a healthcare provider before use, especially during pregnancy.
Q9: Can punicalagin be used in food and beverage applications?
A: Yes. Standardized pomegranate extracts containing 30% punicalagins are used in functional foods, juices, and beverages. The color and flavor profile (characteristic pomegranate aroma) make it suitable for these applications.
Q10: Does punicalagin have any drug interactions?
A: Punicalagin may potentiate the effects of certain medications. As with any supplement, consult a healthcare provider before use, especially if taking anticoagulants, blood pressure medications, or other drugs.
Q11: What is the recommended daily dosage?
A: For standardized extracts (30% punicalagins), typical doses range from 500–1000 mg per day. For high‑purity punicalagin, doses are lower (50–200 mg). Always follow label instructions or consult a healthcare provider.
Q12: Can punicalagin be combined with other antioxidants?
A: Yes. Punicalagin works synergistically with resveratrol, vitamin C, CoQ10, and other polyphenols. Our formulation team can advise on optimal combinations for your product.

 

Test Item Specification (≥98% Grade) Test Result Conclusion
Appearance Faintly yellow to light brown powder Conforms Pass
Assay (HPLC) ≥98.0% 99.2% Pass
Water Content (KF) ≤5.0% 2.8% Pass
Heavy Metals (as Pb) ≤10 ppm <2 ppm Pass
Lead (Pb) ≤1 ppm <0.3 ppm Pass
Total Plate Count ≤1,000 CFU/g <100 CFU/g Pass
E. Coli / Salmonella Negative Negative Pass

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