Strongest Hyaluronic Acid

Strongest Hyaluronic Acid

1.Specification: >= 99.0% (HPLC, on dried basis)
2. Sample: Sample Available
3. Test method: HPLC / Titration / ICP-MS / ¹H-NMR / Elemental analysis
4. Synonyms: L-(+)-Ergothioneine, EGT, ET, 2-Mercaptohistidine trimethylbetaine, Thiasine, Thioneine, Sympectothion, (S)-α-Carboxy-N,N,N-trimethyl-2-mercapto-1H-imidazole-4-ethanaminium inner salt
5. Appearance: White to off-white crystalline powder, odorless
6. Particle size: >95% pass 80 mesh
7. MOQ: 1 KG
8. Package: 1kg/foil bag (double-sealed, light-protected), 25kgs/fiber drum (lined with polyethylene)
9. Certificate: HACCP, ISO 22000, HALAL, GMP, Kosher (available upon request); conforms to USP specifications
10. Molecular Formula: C9H15N3O2S
11. CAS number: 497-30-3
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Description

 

 

hyaluronic acid powder

Our brand Landnutra supplies a high‑purity strongest hyaluronic acid powder - an ultra‑high‑molecular‑weight sodium hyaluronate, standardized to ≥2.0 MDa by viscometry and ≥99% purity by HPLC, engineered to deliver maximum moisture binding, film‑forming capacity, and skin surface smoothing without leaving a sticky residue. Produced via microbial fermentation under full cGMP, this fine white powder dissolves into a viscous, crystal‑clear gel in water, offering a neutral sensory profile that fits clean‑label cosmetic serums, creams, masks, and functional supplements - the preferred choice for formulators sourcing bulk strongest hyaluronic acid powder with uncompromising consistency.

Specification: Molecular Weight ≥2.0 MDa, Purity ≥99.0% (HPLC)
Sample: Sample Available
Test method: Viscometry / HPLC / ICP‑MS / pH
Synonyms: Ultra‑high‑molecular‑weight sodium hyaluronate, HA, high‑viscosity HA powder
MOQ: 1 KG | Package: 1kg/aluminum foil bag (double‑sealed), 25kgs/fiber drum
Certificate: HACCP, ISO 22000, HALAL, GMP, Kosher (available upon request)
Source: Streptococcus zooepidemicus fermentation | CAS: 9067-32-7

hyaluronic acid powder
Product Characteristics
 
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Appearance

Fine, free‑flowing white to off‑white powder, practically odorless.

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Purity

≥99.0% sodium hyaluronate (HPLC), molecular weight ≥2.0 MDa - ensuring maximum viscosity and water‑binding capacity.

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Solubility

Hydrates slowly in cold water to form a highly viscous, transparent gel; pre‑dispersion in glycerol or a vortex mixing step accelerates dissolution.

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pH (1% Solution)

6.0 – 7.5, neutral and skin‑compatible, ideal for leave‑on and rinse‑off products.

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Particle Size

≥95% through 80 mesh; micronized versions available for easier wetting and reduced lumping.

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GMP Manufacturing

Produced via a proprietary fermentation process under cGMP; full traceability from fermentation broth to finished powder.

Benefits of hyaluronic acid powder

1 Maximum Water Retention
With a molecular weight exceeding 2.0 MDa, a single gram of this powder can bind up to six litres of water, forming a breathable hydration reservoir on the skin's surface that immediately smooths fine dryness lines.

2 Superior Film‑Forming & Protective Barrier
The ultra‑long polymer chains create a flexible, non‑occlusive film that reduces transepidermal water loss while allowing gas exchange - perfect for barrier‑support creams and post‑procedure care.

3 Clean, Vegan & Non‑GMO
Derived entirely from microbial fermentation, this ingredient carries no animal‑origin components and meets vegan, Halal, and Kosher requirements, simplifying clean‑label documentation.

4 Broad Formulation Compatibility
Compatible with non‑ionic and most anionic surfactants, as well as common thickeners, humectants, and preservatives; also stable across a wide pH range (4–9), making it suitable for serums, gels, and emulsions.

5 Proven Skin Tolerance
Non‑sensitising and non‑comedogenic; clinical patch tests confirm an excellent safety profile even at high usage levels, supporting claims for products designed for sensitive and reactive skin.

6 Synergistic with Active Ingredients
Its hydrating film can enhance the penetration of co‑formulated actives such as niacinamide, vitamin C, and peptides by maintaining a hydrated stratum corneum, boosting overall formula efficacy.

Application Fields

Skincare (Hero Application): Anti‑aging serums, hydrating boosters, sheet mask essences, eye gels, and day creams (typical use 0.1%–1.0%).

Body & Sun Care: After‑sun gels, body lotions, and soothing mists leveraging the powder's cooling hydration.

Hair & Scalp Care: Conditioners and scalp treatments where a lightweight, non‑greasy film improves moisture retention and manageability.

Medical Devices & Wound Care: Used as a lubricious, moistening component in hydrogel dressings, ophthalmic drops, and surgical aids - meeting pharmacopoeia requirements for endotoxin control.

Nutricosmetics & Supplements: Formulated into oral beauty powders and capsules to support skin hydration from within, often combined with collagen peptides and vitamins.

Production Process

hyaluronic acid powder process

Selected bacterial strains are cultivated in a sterile fermenter, producing sodium hyaluronate extracellularly. The broth is clarified, and the high‑molecular‑weight polymer is isolated via precipitation, then re‑dissolved and purified through a series of filtration steps to remove cells, proteins, and endotoxins. Final spray drying or lyophilisation yields a fine powder with tightly controlled viscosity and purity. All steps are continuously monitored under cGMP. 

Product Quality Advantage

Exceptional Molecular Weight: ≥2.0 MDa, delivering the highest achievable viscosity for surface hydration
High Purity: ≥99% with protein <0.1%, minimising irritation risk
Ultra‑Low Endotoxins: <0.05 EU/mg, suitable for ophthalmic and implant‑grade formulations
Excellent Batch‑to‑Batch Consistency: Viscosity, MW, and purity verified per batch
Stable Under Standard Storage: 24‑month shelf life when kept sealed and dry
Full Regulatory Support: Documentation meets EU CosIng, IECIC, and USP standards
hyaluronic acid powder factory
hyaluronic acid powder Quality Control LabAnnual Capacity: 1,500 Tons | 15+ years of cosmetic active ingredient expertise

Professional ODM/OEM Services

Your Brand, Powered by Strongest Hyaluronic Acid - Backed by Landnutra.

We provide full‑service finished product manufacturing with Strongest Hyaluronic Acid Powder as the core hydrating active.

① Finished Skincare Forms

Serums & Ampoules: Pure HA serums (0.5%–1.0%), multi‑molecular‑weight blends, tinted ampoules

Creams & Gels: Gel‑cream moisturisers, eye gels, sleep masks

Sheet Masks: Bulk‑packed, single‑use face and neck masks with custom bio‑cellulose or cotton sheets

Oral Beauty Powders: Stick packs blending HA with collagen, biotin, and vitamin C

② Specialised Formats
Multi‑weight HA blends (combining 2.0 MDa, 1.0 MDa, and 200 kDa) for layered hydration.

③ Additional Services
Formula development, viscosity tuning, preservative challenge testing, third‑party certifications (Kosher, HALAL, NSF), stability studies, and regulatory dossier preparation.

For a tailored strongest hyaluronic acid powder quotation or OEM project discussion, contact 📧 Email: wangjing@landnutra.com or 📱 WhatsApp: +86 18092657549 - we respond within one business day with complete technical data.

FAQ

Q1: What makes this the "strongest" hyaluronic acid powder?
A1: It refers to the ultra‑high molecular weight (≥2.0 MDa) - the highest available commercially - which provides superior water‑binding and film‑forming properties compared to lower‑MW grades, delivering intense surface hydration.
Q2: How do you control molecular weight from batch to batch?
A2:We use strict in‑process fermentation and purification controls, and every batch is tested by viscometry to confirm MW before release. A viscosity specification ensures consistency.
Q3: Is this powder suitable for clear gel products?
A3: Yes. It hydrates to form a completely transparent, viscous gel, perfect for crystal‑clear serums and toners. A pre‑dispersion step is recommended to avoid lumps.
Q4:Can I combine it with lower‑molecular‑weight HA?
A4: Absolutely. Many brands use a multi‑weight blend for both surface and deeper hydration. We can supply the complementary low‑MW grade under the same quality system.
Q5: What is the recommended usage level in a serum?
A5: Typically 0.2%–0.5% of this high‑MW powder yields a viscous, smooth serum. For ultra‑thick gels, up to 1.0% can be used. We provide formulation guidance based on your target texture.
Q6:  Does it work in anhydrous formulations?
A6: It is water‑soluble and not suitable for pure oil‑based systems. For anhydrous sticks or balms, we recommend pre‑hydrating the powder in a small amount of water phase before emulsification.

 

Test Item Specification (USP Grade) Test Result Conclusion
Appearance White to off‑white powder Conforms Pass
Assay (Sodium Hyaluronate, HPLC) ≥99.0% 99.3% Pass
Molecular Weight (Viscometry) ≥2.0 MDa 2.2 MDa Pass
pH (1% solution) 6.0 – 7.5 6.7 Pass
Loss on Drying ≤10.0% 6.5% Pass
Protein Content ≤0.1% 0.03% Pass
Heavy Metals (as Pb) ≤10 ppm <2 ppm Pass
Lead (Pb) ≤1.0 ppm <0.2 ppm Pass
Arsenic (As) ≤1.0 ppm <0.2 ppm Pass
Total Aerobic Count ≤100 cfu/g <10 cfu/g Pass
E. Coli / Salmonella Negative Negative Pass

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