LANDNUTRA Hyaluronic Acid Powder is a premium ultra-high-molecular-weight sodium hyaluronate, standardised to ≥2.0 MDa by viscometry and ≥99% purity by HPLC, engineered to deliver maximum moisture binding, film-forming capacity, and skin surface smoothing without leaving a sticky residue. This fine white powder, produced via microbial fermentation under full cGMP, dissolves into a viscous, crystal-clear gel in water, offering a neutral sensory profile that fits clean-label cosmetic serums, creams, masks, and functional supplements.
As a professional manufacturer and supplier of high-purity cosmetic actives, LANDNUTRA produces this pure hyaluronic acid through a proprietary fermentation process using Streptococcus zooepidemicus, ensuring consistent molecular weight and exceptional purity with protein content below 0.1%. Available in bulk quantities with ultra-low endotoxin levels (<0.05 EU/mg) suitable for ophthalmic and implant-grade applications, our hyaluronic acid powder meets USP, EU CosIng, and IECIC standards. Every batch is rigorously tested for molecular weight, purity, heavy metals, and microbial contamination, with full traceability from fermentation broth to finished powder - the quality assurance that cosmetic and pharmaceutical brands require for global market entry.
Specification: ≥99.0% (HPLC) · Molecular Weight ≥2.0 MDa · CAS: 9067-32-7
Sample: Available upon request · MOQ: 1 KG · Package: 1kg/foil bag, 25kg/fiber drum
Product Characteristics
Specifications & Physical Properties
Appearance & Sensory
Fine, free-flowing white to off-white powder, practically odorless. Dissolves to form a crystal-clear, viscous gel.
Purity & Molecular Weight
≥99.0% sodium hyaluronate (HPLC) with molecular weight ≥2.0 MDa - ensuring maximum viscosity and water-binding capacity.
Solubility & Hydration
Hydrates slowly in cold water to form a highly viscous, transparent gel. Pre-dispersion in glycerol or vortex mixing accelerates dissolution and minimises lumping.
pH (1% Solution)
6.0 – 7.5 - neutral and skin-compatible, ideal for leave-on and rinse-off products across all skin types.
Particle Size Options
≥95% through 80 mesh (standard). Micronised versions available for easier wetting and reduced lumping in high-speed blending.
GMP Manufacturing & Traceability
Produced via proprietary fermentation under cGMP. Full traceability from fermentation broth to finished powder with complete documentation.
COA (Certificate of Analysis)
|
Test Item |
Specification |
Typical Result |
Test Method |
|
Appearance |
White to off-white powder |
Conforms |
Visual |
|
Odor |
Practically odorless |
Conforms |
Organoleptic |
|
Assay (Sodium Hyaluronate, HPLC) |
≥ 99.0% |
99.3% |
HPLC |
|
Molecular Weight (Viscometry) |
≥ 2.0 MDa |
2.2 MDa |
Viscometry |
|
pH (1% solution) |
6.0 – 7.5 |
6.7 |
Potentiometric |
|
Loss on Drying |
≤ 10.0% |
6.5% |
Karl Fischer |
|
Protein Content |
≤ 0.1% |
0.03% |
Bradford Assay |
|
Endotoxin (LAL) |
≤ 0.05 EU/mg |
< 0.05 EU/mg |
LAL |
|
Heavy Metals (as Pb) |
≤ 10 ppm |
< 2 ppm |
ICP-MS |
|
Lead (Pb) |
≤ 1.0 ppm |
< 0.2 ppm |
ICP-MS |
|
Arsenic (As) |
≤ 1.0 ppm |
< 0.2 ppm |
ICP-MS |
|
Total Aerobic Count |
≤ 100 cfu/g |
< 10 cfu/g |
USP <61> |
|
E. coli / Salmonella |
Negative |
Negative |
USP <62> |
Product Benefits
Why Formulators Choose Ultra-High-Molecular-Weight Hyaluronic Acid
Maximum Water Retention
With a molecular weight exceeding 2.0 MDa, a single gram of this powder can bind up to six litres of water, forming a breathable hydration reservoir on the skin's surface that immediately smooths fine dryness lines.
01
Superior Film-Forming & Protective Barrier
The ultra-long polymer chains create a flexible, non-occlusive film that reduces transepidermal water loss while allowing gas exchange - perfect for barrier-support creams and post-procedure care.
02
Clean, Vegan & Non-GMO
Derived entirely from microbial fermentation, this ingredient carries no animal-origin components and meets vegan, Halal, and Kosher requirements, simplifying clean-label documentation.
03
Broad Formulation Compatibility
Compatible with non-ionic and most anionic surfactants, as well as common thickeners, humectants, and preservatives. Stable across a wide pH range (4–9), suitable for serums, gels, and emulsions.
04
Proven Skin Tolerance & Synergy with Actives
Non-sensitising and non-comedogenic; clinical patch tests confirm excellent safety. Its hydrating film enhances penetration of co-formulated actives such as niacinamide, vitamin C, and peptides.
05
Production Process
Manufacturing Workflow: Bacterial Strain Cultivation (Streptococcus zooepidemicus) → Sterile Fermentation → Broth Clarification → Precipitation → Re-dissolution & Purification (multistage filtration) → Endotoxin Removal → Spray Drying / Lyophilisation → Milling & Sieving → Quality Control Testing → Packaging.
Selected bacterial strains are cultivated in a sterile fermenter, producing sodium hyaluronate extracellularly. The broth is clarified, and the high-molecular-weight polymer is isolated via precipitation, then re-dissolved and purified through a series of filtration steps to remove cells, proteins, and endotoxins. Final spray drying yields a fine powder with tightly controlled viscosity and purity. As a manufacturer with 15+ years of fermentation-derived active ingredient expertise, we guarantee consistent molecular weight and exceptional purity across every batch.
Product Quality Advantages
Exceptional Molecular Weight: ≥2.0 MDa, delivering the highest achievable viscosity for surface hydration and film-forming performance.
High Purity: ≥99% with protein content below 0.1%, minimising irritation risk and ensuring clean-label compliance.
Ultra-Low Endotoxins: <0.05 EU/mg, suitable for ophthalmic and implant-grade formulations requiring stringent purity standards.
Excellent Batch-to-Batch Consistency: Viscosity, molecular weight, and purity verified per batch by validated analytical methods.
Stable Under Standard Storage: 24-month shelf life when kept sealed in a cool, dry environment - protected from moisture and light.
Full Regulatory Support: Documentation meets EU CosIng, IECIC, and USP standards, supporting global market compliance.
Application Fields
Skincare (Hero Application): Anti-aging serums, hydrating boosters, sheet mask essences, eye gels, and day creams (typical use 0.1%–1.0%).
Body & Sun Care: After-sun gels, body lotions, and soothing mists leveraging the powder's cooling hydration and barrier-support properties.
Hair & Scalp Care: Conditioners and scalp treatments where a lightweight, non-greasy film improves moisture retention and manageability.
Medical Devices & Wound Care: Used as a lubricious, moistening component in hydrogel dressings, ophthalmic drops, and surgical aids - meeting pharmacopoeia requirements.
Nutricosmetics & Supplements: Formulated into oral beauty powders and capsules to support skin hydration from within, often combined with collagen peptides and vitamins.
Professional ODM/OEM Services
Your Brand, Powered by Ultra-High-Molecular-Weight Hyaluronic Acid - Backed by LANDNUTRA.
We provide full-service finished product manufacturing with hyaluronic acid powder as the core hydrating active, supporting you from concept to commercial production.
Serums & Ampoules: Pure HA serums (0.5%–1.0%), multi-molecular-weight blends, and tinted ampoules for targeted hydration.
Creams & Gels: Gel-cream moisturisers, eye gels, and sleep masks with custom viscosity and texture profiles.
Sheet Masks: Bulk-packed, single-use face and neck masks with custom bio-cellulose or cotton sheets.
Oral Beauty Powders: Stick packs blending HA with collagen, biotin, and vitamin C for beauty-from-within formulations.
Specialised Formats: Multi-weight HA blends (combining 2.0 MDa, 1.0 MDa, and 200 kDa) for layered hydration strategies.
Additional Services: Formula development, viscosity tuning, preservative challenge testing, third-party certifications (Kosher, HALAL, NSF), stability studies, and regulatory dossier preparation.
Contact: wangjing@landnutra.com | WhatsApp: +86 18092657549
Why Choose LANDNUTRA Hyaluronic Acid Powder?
Proprietary Fermentation Expertise
With 15+ years of microbial fermentation experience, we control every step from strain selection to finished powder - ensuring consistent molecular weight and exceptional purity.
Superior Quality Control
Our cGMP-certified facility is equipped with HPLC, viscometry, and ICP-MS. Every batch is tested for molecular weight, purity, proteins, and endotoxins.
Global Regulatory Compliance
HACCP, ISO 22000, GMP, Halal, and Kosher certifications. Documentation meets EU CosIng, IECIC, and USP standards for smooth market entry.
Flexible Supply & Customisation
From 1-kg evaluation samples to commercial-scale bulk orders. We offer standard and micronised particle sizes, custom molecular weight grades, and pre-blends.
Full Formulation Support
Our team provides hydration optimisation guidance, viscosity tuning, and preservative compatibility testing - we reply to all inquiries within one business day.
Premium Market Positioning
As a trusted supplier to the global cosmetic and pharmaceutical markets, we help brands differentiate with ultra-high-purity hyaluronic acid that meets the highest standards of quality and efficacy.
Export Certificates
LANDNUTRA holds full global certifications and provides complete verified documents for smooth worldwide customs clearance. As a premier supplier of high-purity cosmetic and pharmaceutical actives to the global market, we ensure every batch meets international safety and quality standards.
FAQ
Q: What makes this the "strongest" hyaluronic acid powder?
A: It refers to the ultra-high molecular weight (≥2.0 MDa) - the highest available commercially - which provides superior water-binding and film-forming properties compared to lower-MW grades, delivering intense surface hydration.
Q: How do you control molecular weight from batch to batch?
A: We use strict in-process fermentation and purification controls, and every batch is tested by viscometry to confirm MW before release. A viscosity specification ensures consistency.
Q: Is this powder suitable for clear gel products?
A: Yes. It hydrates to form a completely transparent, viscous gel, perfect for crystal-clear serums and toners. A pre-dispersion step is recommended to avoid lumps.
Q: Can I combine it with lower-molecular-weight HA?
A: Absolutely. Many brands use a multi-weight blend for both surface and deeper hydration. We can supply complementary low-MW and mid-MW grades under the same quality system.
Q: What is the recommended usage level in a serum?
A: Typically 0.2%–0.5% of this high-MW powder yields a viscous, smooth serum. For ultra-thick gels, up to 1.0% can be used. We provide formulation guidance based on your target texture.
Q: Does it work in anhydrous formulations?
A: It is water-soluble and not suitable for pure oil-based systems. For anhydrous sticks or balms, we recommend pre-hydrating the powder in a small amount of water phase before emulsification.
Worldwide Delivery, Arranged for You
We deliver our ingredients to customers across global markets, choosing the most suitable shipping solution for every order and providing complete documentation along the way. Every delivery is handled end to end, with our team staying with the shipment until it reaches you.
Global Presence Through Industry Events
We regularly take part in international industry exhibitions to meet partners, share expertise and stay close to market trends. Details of our upcoming events are available on request.
Partnerships Built on Results
We work with brands and manufacturer partners across different markets and categories, supporting them from sample stage to commercial bulk supply. Specific references and case details are shared directly with qualified customers upon request.
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