introduction
Our L 5 methyltetrahydrofolate powder, also known as active folate 5-MTHF raw material, presents pale off-white fine crystals, with good water solubility for compound processing of dietary supplements; This USP-grade active vitamin B9 raw material boasts far higher bioavailability than ordinary folic acid, with no extra enzymatic conversion required inside the human body, enabling faster absorption; It works well for people with MTHFR gene mutations, without bringing extra metabolic burdens, serving as the preferred raw material for prenatal multivitamins and methylated B-vitamin formulas; Multi-layer precise purification technology strictly controls impurities, maintaining steady purity above 99%, with ultra-low heavy metal and solvent residues, fully complying with strict standards for food-grade and nutraceutical raw materials; The powder has fine, uniform particle size and outstanding dispersibility, free from agglomeration, and strong mixing compatibility, applicable to full-range production lines of capsules, tablets and solid powder products; This raw material effectively regulates homocysteine levels in the human body, supports healthy fetal neural tube development, and suits formulation development of daily brain nourishment supplements; It resists oxidation and deterioration during storage, retaining its original activity for a long time under normal-temperature sealed storage, which greatly extends the shelf life of finished goods; It has no pungent odor, and will not trigger discoloration or efficacy loss when blended with other vitamins and minerals, delivering superior formula compatibility.
Product Characteristics
Active bioavailable B9 nutrient – bypasses metabolic conversion, ideal for MTHFR variant users, supports prenatal & cardiovascular health.
High purity, stable performance – multi-stage refined purification, ≥99% assay, uniform batch-to-batch quality.
Good water dispersibility – fine crystalline powder, no agglomeration, smooth mixing for tablet, capsule & powder formulas.
Safe & compliant raw material – low heavy metal & solvent residues, complete COA, TDS, MSDS certification files provided.
Wide application range – fits prenatal multivitamins, methyl B-complex, brain care & homocysteine balancing supplements.
COA
|
Item |
Specification |
Test Result |
|---|---|---|
| Product Name | L 5 Methyltetrahydrofolate Powder (5-MTHF, L-Methylfolate Calcium) | Conforms |
| Assay (L 5 Methyltetrahydrofolate Content) | ≥99.0% (HPLC/UV) | 99.2% |
| Loss on Drying | ≤0.5% | 0.2% |
| Residue on Ignition | ≤0.1% | 0.05% |
| Heavy Metals (as Pb) | ≤10 ppm | <5 ppm |
| Arsenic (As) | ≤2 ppm | <1 ppm |
| Lead (Pb) | ≤1 ppm | <0.5 ppm |
| Total Microbial Count | ≤1000 CFU/g | <100 CFU/g |
| Yeast & Mold | ≤100 CFU/g | <10 CFU/g |
| E. Coli | Negative in 10g | Negative |
| Salmonella | Negative in 25g | Negative |
Benefits of L 5 Methyltetrahydrofolate Powder
- High bioavailability active B9, no metabolic conversion needed, perfect for MTHFR-sensitive formulations and prenatal vitamin lines.
- Ultra-high purity fine crystal powder, free of caking, compatible with capsules, tablets and bulk powder supplements.
- Stable oxidation-resistant structure, extends finished product shelf life and reduces waste during production storage.
- Low heavy metal & microbial indexes, full supporting documents (COA/MSDS/TDS) to meet global food safety certification demands.
- Wide formula compatibility, mixes smoothly with methyl B complex, homocysteine balancing and brain nutrition raw materials.
Application Fields
Prenatal & Maternal Nutrition
Used in premium prenatal vitamins and pregnancy supplements, especially for individuals with MTHFR gene polymorphisms (folate metabolism disorders).
Clinical Nutrition (FSMP)
Applied in foods for special medical purposes to help lower homocysteine levels; absorption is not affected by gastrointestinal function.
Functional Beverages
Used in powdered drinks and oral liquids, targeting anti-fatigue and mood regulation benefits.
Cognitive Health for Aging Populations
Formulated with DHA and other actives in nutritional powders to support cognitive function and delay age-related memory decline.
Infant Formula & Children's Nutrition
Added to premium infant milk powders; its natural form closely matches that of breast milk folate, offering a safer profile with no unmetabolized folic acid (UMFA) accumulation risk.
Sports Nutrition & Personalized Supplements
Used in post-exercise recovery products and custom formulations based on genetic testing (personalized nutrition).
Production Process
This flowchart shows our full production line of L 5 Methyltetrahydrofolate Powder. Strict purification and quality checks guarantee high-purity, stable, highly absorbable active folate raw material with full compliance documents.
Product Quality Advantages
High purity, consistent batches – multi-stage refined purification, content above 99%, stable quality, tiny differences between production lots.
Formulation-friendly – great water solubility, uniform mixing without caking, compatible with all kinds of compound formulas.
Wide application range – fits prenatal vitamins, methyl B complex, brain care supplements, tablets, capsules and solid powder products.
Clean & safe raw material – low heavy metal and microbe residues, no extra excipients, complete COA, TDS, MSDS supplied.
Reliable absorption efficiency – active folate B9, no metabolic conversion required, suitable for users with MTHFR gene mutation.
Hot-selling wellness ingredient – balances homocysteine, supports fetal neural development, boosts market competitiveness of finished supplements.
Export Certificates
We hold and can provide all necessary documentation for international markets:
Non-GMO Certificate / Statement
HACCP Certificate
ISO 22000 Food Safety Management System Certificate
FDA Facility Registration
Halal & Kosher Certificates (upon request)
Comprehensive Third-Party Laboratory Test Reports (SGS, Eurofins, etc.)
Why choose us
With our own production and tight supply chain, you get consistent, natural, and effective formulas-every time.
We start with materials from certified farms-free from pesticides, heavy metals, and fillers. Every step is documented, so you can trace each ingredient's journey.
We keep investing in better tech and R&D to improve quality and stay innovative. Our supply chain is built to avoid delays-you're never left waiting.
But we're more than a supplier. We're your partner-here to help you succeed for the long run.
If L 5 methyltetrahydrofolate powder aligns with your product development plans, we welcome your enquiry. Our team is ready to provide samples, technical data sheets, and formulation support tailored to your specific needs.
Email: wangjing@landnutra.com
WhatsApp: +86 18092657549
FAQ
Q1: What makes your L 5 methyltetrahydrofolate powder better than regular synthetic folic acid for supplement production?
A: Our L 5 Methyltetrahydrofolate powder is active bioavailable B9, requiring no in-vivo enzymatic conversion; it suits MTHFR gene variant crowds and brings higher absorption rate for prenatal & methyl B-complex formulas, with stable activity during manufacturing and storage.
Q2: Can you provide full official documents to pass global market customs and inspection?
A: Yes, we supply complete COA, TDS, MSDS, plus ISO, HACCP, HALAL, SGS certification copies; all test indicators meet USP standards to satisfy nutraceutical factory registration and overseas customs clearance demands.
Q3: Is your powder suitable for multiple finished product forms?
A: Absolutely, the fine crystalline powder owns excellent dispersibility without agglomeration; it can be evenly blended into capsules, tablets, solid drink powders and compound vitamin premixes without discoloration or efficacy loss.
Q4: What is your MOQ and do you support trial orders for brand testing?
A: Our standard MOQ is 1kg, free small test samples are available for your formula verification; we support flexible batch production, covering small trial batches and long-term large-volume stable bulk supply.
Q5: How do you guarantee consistent batch-to-batch quality for mass production?
A: We adopt multi-layer precise purification and full-process real-time quality monitoring; each batch will undergo HPLC & UV content testing, heavy metal and microbial detection before delivery, to minimize lot-to-lot deviation.
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