Nicotinamide Ribonucleotide (NMN) Powder

Nicotinamide Ribonucleotide (NMN) Powder

Nicotinamide Ribonucleotide (NMN) Powder
1. Specification: ≥ 98.0% – 100.0% (HPLC, on dried basis)
2. Sample: Sample Available
3. Test method: HPLC / LC-MS / NMR / Titration
4. Synonyms: β-Nicotinamide mononucleotide, β-NMN, Nicotinamide mononucleotide, Nicotinamide ribotide, 3-Carbamoyl-1-(5-O-phosphono-β-D-ribofuranosyl)pyridinium
5. Appearance: White to off-white crystalline powder; odorless
6. Particle size: >95% pass 80 mesh
7. MOQ: 1 KG
8. Package: 1kg/foil bag (light-protected), 25kgs/drum
9. Certificate: HACCP, ISO 22000, GMP, Kosher (available upon request)
10. Molecular Formula: C₁₁H₁₅N₂O₈P
11. CAS number: 1094-61-7
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Description


 

Nicotinamide Ribonucleotide (NMN) Powder

Nicotinamide ribonucleotide (NMN) is a naturally occurring nucleotide and a direct precursor to Nicotinamide Adenine Dinucleotide (NAD+) - a vital coenzyme found in every living cell. NAD+ is essential for energy production, DNA repair, and the activation of longevity proteins called sirtuins. As we age, NAD+ levels decline, contributing to metabolic slowdown and age-related decline.

The "Direct NAD+ Precursor" for Cellular Energy: Unlike nicotinamide riboside (NR), which requires phosphorylation to become NMN, NMN is a single enzymatic step away from NAD+. This unique position as a direct precursor means NMN may be more rapidly converted to NAD+ in certain tissues, offering a distinct advantage in NAD+ augmentation strategies.

The Sirtuin Connection: NAD+ is the fuel that powers sirtuins - proteins linked to longevity, stress resistance, and metabolic health. By elevating NAD+ levels, NMN supports sirtuin activation, promoting cellular repair and healthy aging.

Natural Occurrence: NMN is naturally present in small amounts in foods such as edamame, broccoli, avocado, and cucumber seeds. However, dietary intake from these sources is minimal compared to what can be achieved through supplementation.

❄️ Storage Note: NMN is stable under cool, dry conditions (≤25°C, ≤60% RH). Protect from light and moisture. Store in the original sealed container.

Specification: ≥98.0% – 100.0% (HPLC, on dried basis)
Sample: Sample Available
Test method: HPLC / LC-MS / NMR / Titration
Synonyms: β-Nicotinamide mononucleotide, β-NMN, Nicotinamide mononucleotide, Nicotinamide ribotide
MOQ: 1 KG  |  Package: 1kg/foil bag (light-protected), 25kgs/drum
Certificate: HACCP, ISO 22000, GMP, Kosher (available upon request)
Molecular Formula: C₁₁H₁₅N₂O₈P  |  CAS: 1094-61-7

Nicotinamide Ribonucleotide (NMN) Powder
Product Characteristics
 
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Appearance

White to off-white crystalline powder; odorless.
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Purity

≥98% – 100% (HPLC) - high-purity NAD+ precursor.

NAD+ Precursor

Direct precursor - one enzymatic step from NAD+.
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Solubility

Freely soluble in water - ideal for beverages.
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Particle Size

>95% pass 80 mesh.
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GMP Manufacturing

Enzymatic synthesis with full traceability.

COA (Certificate of Analysis)

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Benefits of Nicotinamide Ribonucleotide (NMN) Powder

01NAD+ Elevation - Direct Precursor

NMN is a direct precursor to NAD+ - one enzymatic step away. Supplementation increases cellular NAD+ levels, supporting energy metabolism, DNA repair, and sirtuin activation.

02Cellular Energy & Metabolism

NAD+ is essential for converting food into energy. Increased NAD+ supports healthy mitochondrial function, improves oxidative metabolism, and may protect against metabolic abnormalities.

03Promotes Healthy Aging

NAD+ is a substrate for sirtuins - proteins linked to longevity and stress resistance. By boosting NAD+, NMN supports cellular repair, DNA integrity, and healthy aging.

04Neuroprotective Potential

NMN may support brain health and cognitive function by enhancing NAD+ availability in neural tissues. Supports cerebral perfusion and protects against age-related cognitive decline.

05Metabolic Health Support

Research indicates NAD+ precursors may improve glucose homeostasis, enhance insulin sensitivity, and reduce lipid levels.

06Versatile Applications

Available in ≥98% purity, freely soluble in water - suitable for capsules, powder blends, beverages, and (in some jurisdictions) cosmetic formulations.

Application Fields

Dietary Supplements (Hero Application): Capsules & tablets (125–500 mg), powdered drink mixes, gummies & chewables, multivitamin blends.
Research & Clinical Applications: NAD+ metabolism studies, aging & longevity research, metabolic disorder research.
Cosmetics (Regulatory Specific): Moisturizing & anti‑aging skincare - in China, permitted at up to 3.3% in creams, serums, and masks (excluding sprays and lip products).
OEM Finished Products: Cellular energy capsules, longevity stack (with resveratrol), NAD+ booster powder sticks, energy gummies, skincare serums - full custom manufacturing available.

Production Process

Production process of Nicotinamide Ribonucleotide

Process: D-ribose phosphorylation → enzymatic coupling with nicotinamide (NAMPT) → ion‑exchange chromatography → column chromatography → crystallization → gentle drying → milling → sieving → packaging.

Product Quality Advantage

≥98% – 100% Purity – High-potency NMN.

Direct NAD+ Precursor – One enzymatic step from NAD+.

Freely Soluble in Water – Ideal for beverages and liquids.

Low Heavy Metals – Pb <0.3 mg/kg, As <0.5 mg/kg.

NMR Verified Identity – Confirmed structural integrity.

cGMP Certified – Full traceability and documentation.

Enzymatic Synthesis Facility
Quality Control Lab

Annual Capacity: 1,500 Tons | 15+ years of NAD+ precursor expertise

Professional ODM/OEM Services

We provide full OEM/ODM manufacturing for finished products using Nicotinamide Ribonucleotide as the active ingredient - from concept to commercial delivery, all under one roof.

① Finished Dosage Forms
Capsules: 125 mg, 250 mg, 500 mg; vegetarian/gelatin; custom bottle/blister.
Tablets: Direct compression; round/oval; debossing.
Chews & Gummies: Custom flavors, sugar‑free options.
Powder Blends: Stick packs, tubs; with resveratrol, pterostilbene.
Liquids: Solutions, ready‑to‑drink.
Cosmetics: Serums, creams, masks (where regulated).
Bars: Protein bars, snack bars.

② Combination Options
NMN + Resveratrol (SIRT1 synergy), NMN + Pterostilbene (longevity), NMN + NR (dual NAD+ pathway).

③ Additional Services
Flavor development, third‑party certification (NSF, Informed Sport, Kosher, HALAL), stability testing, regulatory documentation.

📧 Email: wangjing@landnutra.com

📱 WhatsApp: +86 18092657549

All backed by LANDNUTRA's quality assurance - full GMP, Halal, Kosher, COA certification and complete traceability from sourcing to finished product.

Export Certificates

Certificates HACCP ISO GMP Kosher

Why choose us

XI'AN LANDNUTRA CO., LTD. – Your Trusted Manufacturer of Functional Ingredients. Rooted in Quality, Driven by Expertise, Committed to Health and Excellence.

Strong Production Capability: Annual capacity 1,500 tons. 15+ years experience, own facility.
Leading Service: ONE-STOP OEM/ODM from pre-sales to after-sales.
Quality Assurance: CQC-certified enterprise, purity embedded in every process.
Broad Market: Botanical Extracts, Cosmetic Ingredients, Functional Ingredients.

15+ years of experience in functional ingredients and NAD+ precursors. Vertically integrated from raw material sourcing to finished goods manufacturing. Batch‑specific COA including HPLC assay, NMR/LC-MS identification, heavy metals, pH, water content, and microbial limits. Technical support for formulation and stability.

FAQ

Q1: What is the difference between Nicotinamide Ribonucleotide (NMN) and Nicotinamide Riboside (NR)?
A: NMN is a direct precursor to NAD+, requiring just one enzymatic step to convert to NAD+. NR requires phosphorylation to become NMN before it can be converted to NAD+. This makes NMN a more direct NAD+ precursor. NMN has a phosphate group, while NR does not. Both effectively increase NAD+ levels, but through slightly different metabolic pathways.
Q2: What is the recommended dosage?
A: Typical supplemental doses range from 125 mg to 500 mg per day, with some research using up to 1,000 mg per day. For NAD+ support, a common starting dose is 250 mg per day. Always consult a healthcare provider for personalized recommendations.
Q3: Is NMN safe?
A: NMN has an excellent safety profile and has been studied in human trials at doses up to 1,000 mg per day with no significant adverse effects. It is well-tolerated and considered safe for use as a dietary supplement.
Q4: How should NMN be stored?
A: Store in the original sealed container, protected from light, under cool, dry conditions (≤25°C, ≤60% RH). NMN is stable under these conditions for up to 24 months.
Q5: Is NMN vegan?
A: Yes. NMN is synthesized via enzymatic processes using non-animal sources. It does not contain any animal-derived components.
Q6: What is the shelf life?
A: 24 months in original sealed container under cool, dry conditions (≤25°C, ≤60% RH). Once opened, use within 12 months and keep container tightly sealed.
Q7: Can NMN be used in cosmetics?
A: In some jurisdictions, such as China, NMN is permitted as a moisturizing agent in cosmetics at concentrations up to 3.3% in products other than sprays and lip products.
Q8: Is NMN soluble in water?
A: Yes. NMN is freely soluble in water, making it suitable for powder blends, liquid formulations, and beverage applications.
Q9: Can NMN be combined with resveratrol?
A: Yes - this is a common and synergistic combination. NMN boosts NAD+ levels, while resveratrol activates sirtuins (which require NAD+ as a substrate). Together they support cellular health and longevity.
Q10: What is the difference between NMN and NAD+?
A: NMN is a precursor to NAD+. NAD+ is the active coenzyme, but it cannot be taken directly as a supplement (it is not stable and cannot cross cell membranes efficiently). NMN is absorbed and converted to NAD+ inside cells, making it an effective way to raise NAD+ levels.
Q11: Can NMN be used in clear liquid supplements?
A: Yes - NMN is freely soluble in water, making it suitable for clear liquid formulations, ready-to-drink beverages, and powder mixes.
Q12: Is NMN suitable for gummies?
A: Yes - with proper formulation. Its neutral taste and high solubility make it suitable for gummies and chewable supplements.

 

Test Item Specification Test Result Conclusion
Appearance White to off-white powder Conforms Pass
Assay (HPLC) ≥98.0% 98.8% Pass
Identity (NMR) Conforms to reference standard Conforms Pass
pH (10% solution) 2.0 – 4.0 3.2 Pass
Water Content (KF) ≤1.0% 0.6% Pass
Lead (Pb) ≤0.5 mg/kg <0.3 mg/kg Pass
Total Plate Count ≤1,000 CFU/g <100 CFU/g Pass
E. Coli / Salmonella Negative Negative Pass

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