Creatine monohydrate (CM) is the most extensively studied ergogenic aid in the history of sports nutrition. Chemically, it is a nitrogenous organic acid that occurs naturally in vertebrate muscle tissue (approximately 95% of the body's creatine is stored in skeletal muscle). The monohydrate form - containing one molecule of water per molecule of creatine - is the standard, most stable, and most bioavailable form for supplementation.
Chemical Identity & Purity: Our pure creatine monohydrate is manufactured via a controlled synthetic route from sarcosine and cyanamide, followed by crystallization to yield the monohydrate polymorph. The product is then subjected to multiple purification steps (including recrystallization and deionization) to achieve ≥99.95% purity on the dried basis - a specification that meets or exceeds the highest industry standards (including Creapure®-grade equivalency). Impurities such as dicyandiamide, dihydrotriazines, and creatinine are strictly controlled and routinely tested below detectable or specified limits.
Mechanism of Action: In skeletal muscle, creatine is phosphorylated by the enzyme creatine kinase to form phosphocreatine (PCr). Phosphocreatine serves as a rapid, temporal energy buffer, donating a phosphate group to ADP to regenerate ATP during high‑intensity, short‑duration exercise. Supplementation increases intramuscular total creatine stores by 15–40% in most individuals, thereby enhancing power output, accelerating ATP resynthesis, and potentially facilitating muscle protein synthesis.
Regulatory Status: Creatine monohydrate is classified as a dietary ingredient in most jurisdictions, including the United States (FDA GRAS for dietary supplements and certain conventional foods), the European Union, and many other countries.
Quality Distinction: Our product is pharmaceutical-grade in terms of purity and impurity control. Key quality metrics include: water content (≤12.0%), heavy metals (Pb ≤0.5 ppm, As ≤0.5 ppm), dicyandiamide (DCD) ≤10 ppm, and creatinine ≤50 ppm.
Specification: 99.95% – 100.1% (on dried basis)
Sample: Sample Available
Test method: HPLC / Titration / USP method / Karl Fischer (water content)
Synonyms: Creatine monohydrate, N-(Aminoiminomethyl)-N-methylglycine monohydrate, Methylguanidoacetic acid monohydrate
MOQ: 1 KG | Package: 1kg/foil bag, 20kgs/carton, 25kgs/drum
Certificate: HACCP, ISO 22000, HALAL, GMP, Kosher (available upon request)
Molecular Formula: C₄H₉N₃O₂·H₂O | CAS: 6020-87-7
Product Characteristics
Appearance
Purity (Dried Basis)
Water Content
pH (1% suspension)
Particle Size
GMP Manufacturing
COA (Certificate of Analysis)
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Benefits of Pure Creatine Monohydrate Powder
01Enhanced Power & Strength
Multiple meta‑analyses confirm creatine increases maximal power output (1–15%), strength (5–15% improvement in 1RM), and work capacity during repeated sprints or sets.
02Increased Lean Body Mass
Creatine supplementation combined with resistance training consistently increases fat‑free mass (typically 1–3 kg over 4–12 weeks) through cell swelling and enhanced protein synthesis.
03Accelerated Recovery
Reduces muscle damage markers following high‑intensity exercise, leading to faster recovery of strength and reduced soreness.
04Neuroprotective & Cognitive Effects
Preliminary studies suggest creatine may improve short‑term memory and attention in older adults or sleep‑deprived individuals, with emerging research in neurological conditions.
05Metabolic Benefits
May help regulate blood glucose by improving GLUT4 translocation and glycogen storage, particularly when combined with exercise.
06Exceptional Safety & Tolerability
Decades of research, including long‑term studies (up to 5 years), demonstrate that creatine monohydrate at recommended doses (3–5 g/day) is safe in healthy individuals.
Application Fields
Dietary Supplements: Capsules, tablets, chews, liquid creatine, RTD drinks, creatine bars, pure powder (unflavored or flavored), pre‑workout blends, post‑workout recovery blends.
Functional Foods: Sports nutrition bars, meal replacement bars, ready‑to‑mix protein shakes.
Clinical Nutrition / Medical Foods: Muscle‑wasting conditions (sarcopenia, cachexia – investigational), neurological conditions (under professional supervision).
Production Process
Product Quality Advantage
≥99.95% Purity – Pharmaceutical-grade, meets or exceeds Creapure® specifications.
Ultra-Low Impurities – DCD, DHT, creatinine at or below detection limits.
Low Heavy Metals – Pb, As, Cd, Hg <0.5 ppm each.
Standard & Micronized – Both particle sizes available.
Excellent Stability – 24+ months shelf life in dry form.
cGMP Certified – Full traceability and documentation.
Annual Capacity: 1,500 Tons | 15+ years of ingredient production expertise
Professional ODM/OEM Services
We deliver comprehensive OEM/ODM solutions for finished creatine monohydrate products. From concept to finished bottle - we've got you covered.
① Finished Dosage Forms
Capsules: 500 mg, 750 mg, 1000 mg; vegetarian/vegan shells available.
Tablets: Direct compression or wet granulation; instant-release; custom shapes and debossing.
Chews: Soft chews or gummy formats; fruit flavors; sugar‑free options.
Liquid Creatine: Stable pre‑mixed liquid shots or multi‑dose bottles.
RTD Drinks: Bottles, cans, Tetra Pak; isotonic or hypertonic formulations.
Creatine Bars: Protein bars, energy bars with uniform creatine dispersion.
② Powder Blends
Pure creatine powder (unflavored or flavored), pre‑workout blends, post‑workout recovery blends, intra‑workout formulas, single‑serve sachets (stick packs).
③ Private Labeling
Full packaging design and regulatory documentation support. We handle the entire development chain: formula design → raw material sourcing → manufacturing → quality release.
Export Certificates
Why choose us
XI'AN LANDNUTRA CO., LTD. – Your Trusted Manufacturer of Antioxidant & Functional Ingredients. Rooted in Quality, Driven by Expertise, Committed to Health and Excellence.
Strong Production Capability: Annual capacity 1,500 tons. 15+ years experience, own facility.
Leading Service: ONE-STOP OEM/ODM from pre-sales to after-sales.
Quality Assurance: CQC-certified enterprise, purity embedded in every process.
Broad Market: Botanical Extracts, Cosmetic Ingredients, Functional Ingredients.
Over 15 years of manufacturing sports nutrition ingredients. cGMP‑certified facilities. Full traceability. In‑house formulation and OEM/ODM expertise for capsules, tablets, chews, liquids, RTD drinks, and bars. Regulatory support (label reviews, compliance documentation).
FAQ
| Test Item | Specification (High-Purity Grade) | Test Result | Conclusion |
|---|---|---|---|
| Appearance | White crystalline powder | Conforms | Pass |
| Assay (creatine monohydrate, dried basis) | ≥99.95% | 99.97% | Pass |
| Water Content (KF) | 11.5% – 12.5% | 12.0% | Pass |
| pH (1% suspension) | 6.5 – 7.5 | 7.1 | Pass |
| Residue on Ignition | ≤0.1% | 0.04% | Pass |
| Lead (Pb) | ≤0.5 ppm | <0.1 ppm | Pass |
| Arsenic (As) | ≤0.5 ppm | <0.1 ppm | Pass |
| Cadmium (Cd) | ≤0.5 ppm | <0.1 ppm | Pass |
| Dicyandiamide (DCD) | ≤10 ppm | 1.2 ppm | Pass |
| Creatinine | ≤50 ppm | 12 ppm | Pass |
| Total Plate Count | ≤1,000 cfu/g | <100 cfu/g | Pass |
| Yeast & Mold | ≤100 cfu/g | <10 cfu/g | Pass |
| E. Coli / Salmonella | Negative | Negative | Pass |
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