introduction
Oligopeptide-1 powder is a synthetic 53-amino-acid peptide structurally identical to human epidermal growth factor (EGF) – a highly purified, water-soluble active that delivers skin repair, anti-aging, and soothing benefits without compromising formulation stability. It accelerates epidermal regeneration by promoting keratinocyte proliferation and migration, stimulates collagen synthesis to reduce fine lines and improve firmness, and calms redness while supporting barrier recovery on sensitive or compromised skin. Formulators appreciate it for being non-irritating, non-sensitizing, and highly stable across pH 4–8 and standard processing temperatures, compatible with most cosmetic ingredients without special handling. It is fully water-soluble, dissolving quickly in room-temperature water with no heating or co-solvents – simply add to the aqueous phase after the batch cools below 40°C, at recommended active levels of 0.01–0.1% (0.05–0.1% for pronounced efficacy). Our oligopeptide-1 is synthetically produced (animal-free) with ≥95% purity by HPLC, tight batch-to-batch control, and appears as a white to off-white odorless lyophilized powder. Packaging ranges from 1g lab samples to bulk custom sizes, with full COA, MSDS, and stability data provided. If you're formulating serums, creams, ampoules, or medical-grade skincare that demands safe, effective, and stable actives for repair and rejuvenation – oligopeptide-1 is a proven, science-backed workhorse validated by decades of research.
Product Characteristics
1. Appearance
White or off-white powder,Won't affect finished product clarity or texture
2. Solubility
Fully water-soluble – dissolves at room temperature, no heating or co-solvents needed. Insoluble in oils. Works in aqueous and O/W systems.
3. Odor & Safety
Nearly odorless, no fragrance interference. For external use only.
4. Purity & Benefits
Synthetic, animal-free. High purity, low batch variation. Non-irritating, non-sensitizing. Delivers repair, anti-aging, and soothing effects. Ideal for serums, creams, lotions, and medical-grade skincare.
5. Quality Control
HPLC-tested for active content. Full panel: appearance, pH, solids, microbes, heavy metals, clarity. Batch-to-batch consistency guaranteed.
COA
| Item | Specification | Typical Result |
|---|---|---|
| Purity (HPLC) | ≥ 95.0% | 97.2% |
| Loss on Drying | ≤ 5.0% | 2.1% |
| Residue on Ignition | ≤ 1.0% | 0.3% |
| Heavy Metals (as Pb) | ≤ 10 ppm | < 5 ppm |
| Lead (Pb) | ≤ 2 ppm | < 0.5 ppm |
| Arsenic (As) | ≤ 2 ppm | < 1 ppm |
| pH (1% aqueous solution) | 4.0 – 7.0 | 5.8 |
| Total Plate Count | ≤ 100 cfu/g | < 10 cfu/g |
| Yeast & Mold | ≤ 10 cfu/g | < 5 cfu/g |
| E. coli | Negative | Negative |
| Salmonella | Negative | Negative |
| Appearance | White to off-white lyophilized powder | Conforms |
| Solubility | Fully water-soluble, clear solution | Conforms |
| Odor | Odorless or very mild | Conforms |
High purity, batch consistency – synthetic, animal-free, HPLC-verified, low lot-to-lot variation, ready for direct incorporation.
Regulatory ready – complete documentation package, compliant with ISO 22716 and major global cosmetic standards.
Process-friendly, versatile – water-soluble, ambient processing, broad pH/temperature tolerance, compatible with serums, creams, lotions, and medical-grade formats.
Clear efficacy, premium positioning – repair + anti-aging + soothing in one, mild and non-irritating, ideal for upgrading mid-to-high-end skincare and aesthetic product lines.
Application Fields
Serums & Toners – Fully water-soluble for clear, lightweight formulas. No tackiness, easy to formulate.
Creams & Lotions – Stable in O/W emulsions. No impact on texture or processing. Direct addition.
Medical-Grade Skincare – Repair + soothing. Ideal for post-procedure, barrier repair, and sensitive skin lines.
Lyophilized Powders & Ampoules – High purity and rapid solubility. Supports high-concentration active formulations.
Masks – Anti-aging benefits. Reduces fine lines, improves firmness. Compatible with sheet, cream, and gel masks.
Eye Creams – Gentle for delicate eye area. Targets wrinkles and sagging. Non-irritating formula.
Production Process
Product Quality Advantages
High purity, batch-to-batch consistency – synthetic, animal-free, ≥95% by HPLC.
Full regulatory documentation – COA, MSDS, stability data – supports global market access.
Process-friendly – water-soluble, room-temperature addition, no heating or co-solvents.
Versatile – compatible with serums, creams, lotions, ampoules, and medical-grade formats.
Clean & safe – non-irritating, non-sensitizing, no animal-derived materials.
Clinically proven efficacy – repair + anti-aging + soothing in one active.
Export Certificates
Our products are backed by a full set of internationally recognized certifications, including food safety, heavy metal and microbial qualification documents. Every batch supports complete traceability and meets EU, US and global food additive standards.
Why choose us
With in-house production and a fully integrated supply chain, LANDNUTRA guarantees stable, pure and natural product quality for every batch. We source raw materials from certified farms, free of pesticides, heavy metals and fillers. Full-process documentation enables complete ingredient traceability to support your market compliance.
LANDNUTRA consistently invests in advanced technology and R&D to optimize product quality and innovation. Our robust supply chain ensures stable, on-time bulk delivery without delays. More than a raw material supplier, we serve as your reliable long-term strategic partner, dedicated to driving your brand and product success.
If Oligopeptide-1 power aligns with your product development plans, we welcome your enquiry. Our team is ready to provide samples, technical data sheets, and formulation support tailored to your specific needs.
Email: wangjing@landnutra.com
WhatsApp: +86 18092657549
FAQ
Q: Is it safe? Does it cause breakouts?
A: Yes, it is very safe. The CIR has reviewed it multiple times and confirmed its safety for cosmetic use. It is non-irritating, low-allergy, and non-absorbing into the skin. With very low comedogenicity-far gentler than many oils and emulsifiers-it is well-tolerated by most users, including those with sensitive or acne-prone skin. We recommend individual patch testing for extremely clog-prone cases.
Q: What is the recommended usage level?
A: Typical dosage depends on target viscosity: 0.5–1.5% for thin lotions, 1–3% for regular creams, 3–5% for thick balms, and 1–3% for conditioners. Exceeding the recommended range may result in heavy feel or poor spreadability. We advise staying within these guidelines for optimal performance.
Q: How is it incorporated into formulations?
A: It is not water-soluble and requires heat for proper incorporation. Add it to the oil phase or oil-water mixture, heat to 65–75°C until fully melted, then homogenize or stir. Upon cooling, it recrystallizes to provide structural integrity to the cream. Avoid cold mixing, as it will clump and fail to disperse.
Q: Does it have any incompatibilities?
A: It is broadly compatible with most oils, emulsifiers, thickeners, and preservatives, and works well across anionic, cationic, and non-ionic systems. Prolonged heating with strong acids or bases should be avoided, though such conditions are rarely encountered in standard production. Overall, it is a highly versatile ingredient.
Q: What are its benefits in conditioners?
A: It delivers smoothness, anti-static effects, and improved combability. It is fully compatible with cationic conditioners such as polyquats and behentrimonium chloride, with no antagonistic interactions. It serves as a primary fatty component in many cost-effective conditioner formulations.
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