Sialic Acid N Acetylneuraminic Acid Powder

Sialic Acid N Acetylneuraminic Acid Powder

Lion's Mane Fruiting Body Extract Powder
1. Specification: 10% – 40% Polysaccharides (UV/HPLC), 10:1 – 15:1 Extract Ratio, Beta-Glucans ≥ 10%, Hericenones (standardized markers)
2. Sample: Sample Available
3. Test method: HPLC / UV-Vis / HPTLC / LC-ESI-QTOF-MS
4. Synonyms: Hericium erinaceus extract, Lion's Mane mushroom fruiting body powder, Yamabushitake extract, Monkey Head mushroom extract, Fruiting body concentrate
5. Appearance: Fine, free‑flowing light brown to dark brown powder; characteristic mushroom odor and taste
6. Particle size: >95% pass 80 mesh
7. MOQ: 1 KG
8. Package: 1kg/foil bag (light‑protected), 25kgs/drum
9. Certificate: HACCP, ISO 22000, HALAL, GMP, Kosher (available upon request), Organic (available upon request)
10. Active Compounds: Polysaccharides (β-glucans: glucose and galactose at molar ratios 3.4–14:1.0), Hericenones C–H (0.43% w/w, expressed as hericenone C relative content), Hericenes, Ergosterol, Ergothioneine, Phytoestrogens (daidzein, genistein)
11. CAS number (Polysaccharide reference): Variable (polydisperse complex)
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Description

 

Sialic Acid N Acetylneuraminic Acid Powder

Our brand Landnutra supplies sialic acid n acetylneuraminic acid powder - a fermentation‑derived, human‑identical monosaccharide standardized to ≥98% purity that functions as a terminal sugar on glycoproteins and glycolipids, influencing cell‑cell recognition, neural development, and anti‑inflammatory pathways. This is the same Neu5Ac that dominates human milk oligosaccharides and brain gangliosides, which is why it is being adopted by formulators of infant nutrition, cognitive‑health supplements, and premium anti‑aging skincare. Every batch is produced under full cGMP using a non‑GMO microbial strain, purified through ion‑exchange chromatography, and dried to a moisture level below 0.5% before being vacuum‑packed in light‑protected foil. For R&D groups exploring new product concepts, we provide a technical dossier that includes an NMR‑verified structure report, a residual‑endotoxin certificate (routinely <0.05 EU/mg), and a forced‑degradation study that maps pH and temperature boundaries - data that helps you move from concept to pilot batch without commissioning external stability work.

Specification: ≥98.0% (HPLC), Neu5Ac content ≥98%, Water ≤0.5%
Sample: Available
Test method: HPLC / NMR / Karl Fischer / ICP‑MS / Endotoxin LAL
Synonyms: N‑Acetylneuraminic acid, Neu5Ac, sialic acid, lactaminic acid, bird's nest extract equivalent
MOQ: 1 KG | Package: 1kg vacuum foil pouch, 25kg fibre drum with desiccant
Certificate: ISO 22000, HACCP, GMP, HALAL, Kosher
Source: Non‑GMO microbial fermentation | CAS: 131-48-6

Sialic Acid N Acetylneuraminic Acid Powder
Product Characteristics
 
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Appearance

white to off‑white crystalline powder, free‑flowing, with no off‑odour and a mildly sweet‑acidic taste.
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Purity & Identity

Neu5Ac assay ≥98% (HPLC); identity confirmed by NMR to match the human endogenous form; no inactive anomers or synthetic isomers.
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pH (1% Solution)

2.5–3.5, reflecting its natural acidity; easily buffered in final formulations or used as a mild acidulant in cosmetic toners.
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Solubility

freely soluble in cold water (≥100 g/L), forming a clear, colourless solution; ideal for transparent functional beverages and liquid shots.
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Particle Size

≥95% through 80 mesh; micronized and agglomerated grades available for improved dispersibility and dust control.
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GMP Manufacturing

produced in a dedicated fermentation and purification suite under ISO 22000; endotoxin and heavy metal testing on every batch.

Benefits Of sialic acid n acetylneuraminic acid powder

01 Brain Development & Cognitive Function

Sialic acid forms key brain gangliosides. It aids synapse growth and learning, ideal for infant nutrition and kids' cognitive supplements.

02 Immune Modulation & Gut Health

Neu5Ac serves as a pathogen decoy on mucosa, blocks bacterial attachment and balances gut immunity, suitable for gut-brain axis formulations.

03 Skin Hydration & Anti‑Glycation

For cosmetics, it strengthens skin glycocalyx, locks moisture and inhibits glycation, boosting elasticity and diminishing fine lines in anti-aging & beauty supplements.

04 Human‑Identical, Low Immunogenic Risk

Our Neu5Ac matches human endogenous structure, without sensitisation risks, safe for long-term oral/topical use for infants and seniors.

05 Fermentation‑Derived, Animal‑Free

Produced via non-GMO microbial fermentation with plant feedstock. Vegan, Halal & Kosher, meets global clean label standards, no bird's nest or animal sources.

06 Customisation & Regulatory Support

Custom particle sizes and pre-blends with DHA, probiotics, collagen. Complete test documents accelerate global product registration.

Application Fields

• Infant Formula & Follow‑on Foods: Simulates human milk sialic acid to support neural and immune development.
• Dietary Supplements: Memory capsules, kids' brain powders and anti‑aging formulations.
• Functional Beverages: Cognitive shots, beauty drinks and focus‑support tonics.
• Cosmetics & Personal Care: Hydrating, anti‑glycation skincare serums, creams and masks.
• Clinical & Medical Nutrition: Enteral formulas for neuro and immune nutritional support.
• Pet Supplements: Cognitive support chews for senior dogs and cats.

Production Process

Sialic Acid N Acetylneuraminic Acid Powder

Non-GMO fermentation yields Neu5Ac, purified, dried, processed and fully tested under cGMP.

Product Quality Advantage

≥98% purity, NMR‑verified as the human‑identical L‑Neu5Ac isomer.

Endotoxin consistently below 0.05 EU/mg, suitable for infant and medical nutrition.

Water‑soluble, crystal‑clear solution - ideal for transparent beverages and liquid supplements.

Animal‑free, non‑GMO, vegan, Kosher, Halal - clean‑label compatible.

Free‑flowing, non‑hygroscopic under standard storage; 24‑month shelf life.

Full documentation: COA, MSDS, NMR report, endotoxin certificate, stability data, and third‑party lab reports.

Sialic Acid N Acetylneuraminic Acid Powder Cultivation Facility
Sialic Acid N Acetylneuraminic Acid Powder Extraction Facility

Annual Capacity: 1,500 Tons | 15+ years of functional mushroom expertise

Professional ODM/OEM Services

Turnkey manufacturing with sialic acid n acetylneuraminic acid powder - backed by Landnutra.

Finished dosage forms: capsules (50–200 mg), direct‑compression tablets, stick packs, clear functional beverages, gummies, and liquid drops.
Popular pre‑blends: sialic acid + DHA (infant cognition), sialic acid + collagen peptides (beauty‑from‑within), sialic acid + probiotics (gut‑brain axis).
Additional services: custom particle size, co‑drying, flavour masking, third‑party certifications (Kosher, HALAL, NSF), ICH‑guided stability studies, and regulatory dossier compilation. For a quotation or sample, contact Email: wangjing@landnutra.com or WhatsApp: +86 18092657549 - response within one business day.

Export Certificates

Sialic Acid N Acetylneuraminic Acid Powder Certificates HACCP ISO HALAL GMP Kosher Organic

 Landnutra owns global certifications. Every sialic acid shipment provides full verified export documentation.

Why choose us

XI'AN LANDNUTRA CO., LTD. manufactures sialic acid n acetylneuraminic acid powder using a dedicated fermentation‑purification line that keeps endotoxin levels well below pharmacopoeial limits - a critical quality attribute for infant and medical nutrition that many bulk suppliers overlook. We also supply DHA algal oil powder and Lactoferrin under the same cGMP‑certified roof, enabling you to consolidate maternal‑infant ingredient sourcing with one audited vendor. For a current sialic acid n acetylneuraminic acid powder price list, a tailored quotation, or a free 20–50 g evaluation sample, contact wangjing@landnutra.com or WhatsApp: +86 18092657549 - we reply within one business day.

FAQ

Q1: What is the typical dosage of sialic acid n acetylneuraminic acid powder in infant formula?
A: To match the sialic acid content of human milk, formulators typically add 100–200 mg per litre of reconstituted formula. Our technical team can provide guidance based on your target market's regulatory limits.
Q2: How does this powder compare to bird's nest extract as a source of sialic acid?
A: Bird's nest extract contains variable and low levels of sialic acid bound to glycoproteins. Our pure Neu5Ac powder delivers a defined, consistent dose with no allergenic or sustainability concerns.
Q3: Is sialic acid n acetylneuraminic acid powder suitable for vegan and Halal products?
A:Yes. It is produced via microbial fermentation without any animal‑derived raw materials or processing aids, and is certified Halal and Kosher.
Q4: Can it be used in clear beverages?
A: Absolutely. It dissolves completely in cold water to form a crystal‑clear, colourless solution, making it ideal for transparent functional drinks and beauty shots.
Q5:What documentation do you provide for regulatory filings?
A: We supply a comprehensive technical dossier including NMR structural confirmation, endotoxin certificate, stability data, heavy metal and microbial reports, and a statement of non‑GMO and vegan status.
Q6: How is the powder stabilised during storage?
A: The powder is dried to ≤0.5% moisture and vacuum‑packed in light‑protective foil with desiccant. Under these conditions, it remains stable for 24 months at room temperature.

 

Test Item Specification (30% Polysaccharides) Test Result
Appearance White to off‑white crystalline powder Conforms
Assay (HPLC, Neu5Ac) ≥98.0% 98.8%
Loss on Drying ≤0.5% 0.22%
Residue on Ignition ≤0.2% 0.04%
pH (1% solution) 2.5–3.5 3.1
Heavy Metals (as Pb) ≤10 ppm <2 ppm
Lead (Pb) ≤1 ppm <0.3 ppm
Arsenic (As) ≤1.0 ppm <0.2 ppm
Cadmium (Cd) ≤0.5 ppm <0.1 ppm
Endotoxin (LAL) ≤0.5 EU/mg <0.05 EU/mg
Total Plate Count ≤1,000 cfu/g <100 cfu/g
E. Coli / Salmonella Negative Negative

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