Description

Alpha GPC Powder

Alpha-GPC (L-alpha-glycerylphosphorylcholine) is a naturally occurring choline compound found in the brain and in food sources such as eggs, dairy, meat, and fish. It is a highly bioavailable source of choline that can cross the blood-brain barrier, serving as a direct biosynthetic precursor to the neurotransmitter acetylcholine.

🧠 The "Bioavailable Choline" for Cognitive and Physical Performance: Alpha-GPC delivers choline to the brain more efficiently than many other choline sources, supporting the synthesis of acetylcholine - a neurotransmitter critical for memory, learning, and muscle function. Additionally, alpha-GPC provides glycerophosphate, which helps support neuronal membrane integrity.

GRAS Status: The FDA has determined that intake of no more than 196.2 mg/person/day is considered Generally Recognized as Safe (GRAS).

💧 Storage Note: Alpha-GPC is highly hygroscopic (especially the 99% grade). Store in the original sealed container under cool, dry conditions (≤25°C, ≤60% RH). Seal tightly after each use to prevent moisture absorption and clumping.

Specification: 50% – 99% (HPLC, various strengths available)
Sample: Sample Available
Test method: HPLC / Potentiometric Titration / USP method
Synonyms: Alpha-GPC, L-Alpha glycerylphosphorylcholine, Choline alfoscerate, Glycerophosphocholine, Choline glycerophosphate
MOQ: 1 KG | Package: 1kg/foil bag, 25kgs/drum
Certificate: HACCP, ISO 22000, GMP, HALAL (available upon request)
Molecular Formula: C₈H₂₀NO₆P | CAS: 28319-77-9

Product Characteristics

🧂

Appearance

White to off-white fine powder; neutral odor.

⚗️

Purity Range

50% – 99% (HPLC) - multiple strengths available.

💧

Solubility

Freely soluble in water - ideal for beverages and liquids.

🧬

Mechanism

Acetylcholine precursor; crosses blood-brain barrier.

📏

Particle Size

>95% pass 80 mesh.

🏭

GMP Manufacturing

Advanced synthesis/extraction with full traceability.

COA (Certificate of Analysis)

Benefits of Alpha GPC Powder

01Cognitive Enhancement

Alpha-GPC rapidly delivers choline to the brain across the blood-brain barrier, serving as a biosynthetic precursor to acetylcholine. Supports memory, learning, and processing speed - even in healthy populations.

02Athletic Performance

Prevents exercise-induced reductions in choline levels, increasing endurance performance and growth hormone secretion. Valuable for pre-workout and recovery formulations.

03Neuroprotection & Healthy Aging

Studied for its potential neuroprotective properties. Supports neuronal membrane integrity, mitochondrial function, and may improve cognition in aging populations.

04Growth Hormone Support

Alpha-GPC administration has been associated with increased growth hormone secretion, supporting muscle recovery and performance.

05Membrane Integrity & Synergy

Unlike some choline sources, alpha-GPC provides both choline and glycerophosphate components, working synergistically to support neuronal membrane integrity and optimize neurotransmitter synthesis.

06Multiple Grades Available

Available in 50% and 99% purity grades to suit various applications - from cost‑effective dietary supplements to premium pharmaceutical-grade formulations.

Application Fields

Dietary Supplements (Hero Application): Capsules & tablets (300–600 mg), powder blends & stick packs, gummies & chewables, multivitamin & nootropic blends.
Sports Nutrition: Pre‑workout formulas, recovery blends.
Clinical Nutrition: Cognitive health formulations for healthy aging.
Pharmaceuticals: API for drug formulations (cognitive health and neurological applications).
OEM Finished Products: Cognitive support capsules, nootropic powder sticks, pre‑workout gummies, focus formula, ready‑to‑mix powder - full custom manufacturing available.

Production Process

Production process of Alpha GPC

Process: Natural or synthetic precursor → enzyme-catalyzed hydrolysis → chromatography purification → crystallization → gentle drying → standardization → milling → sieving → moisture‑proof packaging.

Product Quality Advantage

50% – 99% Purity Range – Multiple grades for formulation flexibility.

Water Soluble – Freely soluble in water for beverages.

Low Heavy Metals – Pb <0.01 ppm, As <0.1 ppm.

High Optical Purity – Confirmed via specific rotation.

GRAS Status – FDA recognized safe.

cGMP Certified – Full traceability and documentation.

Annual Capacity: 1,500 Tons | 15+ years of nootropic ingredient expertise

Professional ODM/OEM Services

We provide full OEM/ODM manufacturing for finished products using Alpha-GPC as the active ingredient - from concept to commercial delivery, all under one roof.

① Finished Dosage Forms
Capsules: 300 mg, 500 mg, 600 mg; vegetarian/gelatin; custom bottle/blister.
Tablets: Direct compression; round/oval; debossing.
Chews & Gummies: Custom flavors, sugar‑free options.
Powder Blends: Stick packs, tubs; with Citicoline, L‑Tyrosine, B‑vitamins.
Liquids: Solutions, ready‑to‑drink.
Bars: Protein bars, snack bars.

② Combination Options
Alpha-GPC + Citicoline (dual choline), Alpha-GPC + L-Tyrosine (focus), Alpha-GPC + Bacopa (cognitive synergy).

③ Additional Services
Flavor development, third‑party certification (NSF, Informed Sport, Kosher, HALAL), stability testing (moisture control), regulatory documentation.

📧 Email: wangjing@landnutra.com

📱 WhatsApp: +86 18092657549

All backed by LANDNUTRA's quality assurance - full GMP, Halal, Kosher, COA certification and complete traceability from sourcing to finished product.

Export Certificates

Certificates HACCP ISO GMP Halal Kosher

Why choose us

XI'AN LANDNUTRA CO., LTD. – Your Trusted Manufacturer of Functional Ingredients. Rooted in Quality, Driven by Expertise, Committed to Health and Excellence.

Strong Production Capability: Annual capacity 1,500 tons. 15+ years experience, own facility.
Leading Service: ONE-STOP OEM/ODM from pre-sales to after-sales.
Quality Assurance: CQC-certified enterprise, purity embedded in every process.
Broad Market: Botanical Extracts, Cosmetic Ingredients, Functional Ingredients.

15+ years of experience in functional ingredients and nootropic compounds. Vertically integrated from raw material sourcing to finished goods manufacturing. Batch‑specific COA including assay, optical rotation, water content, and heavy metals. Technical support for formulation and stability.

FAQ

Q1: What is the difference between 50% and 99% Alpha-GPC powder?

A: The 50% grade is a standardized powder containing 50% alpha-GPC, often with excipients to maintain stability and flowability. It is cost-effective and suitable for most dietary supplement applications. The 99% grade is a highly purified form with minimal excipients, ideal for premium nutraceuticals, pharmaceuticals, and research. Both forms are effective, but the 99% grade offers higher potency per gram.

Q2: What is the recommended dosage?

A: Typical doses range from 300–600 mg per day for cognitive support. As per FDA GRAS determination, intake of no more than 196.2 mg/person/day is considered safe. Some clinical studies have used higher doses (e.g., 1,200 mg) for specific applications. Always consult a healthcare provider for personalized recommendations.

Q3: Is Alpha-GPC better than other choline sources?

A: Alpha-GPC is one of the most bioavailable choline sources, efficiently crossing the blood-brain barrier to deliver choline directly to the brain. Unlike some choline salts, it does not have a fishy odor. It also provides glycerophosphate, which supports neuronal membrane integrity.

Q4: Does Alpha-GPC cause side effects?

A: Alpha-GPC is generally well-tolerated at recommended doses. Some individuals may experience mild gastrointestinal upset, headache, or insomnia if taken close to bedtime. It should not be combined with cholinergic drugs without medical supervision.

Q5: Is Alpha-GPC vegan?

A: Our Alpha-GPC can be sourced from non-animal origins (e.g., soy lecithin or synthetic production). Please confirm specific batch sourcing for vegan suitability.

Q6: Why does 99% Alpha-GPC clump easily?

A: High-purity Alpha-GPC (99%) is highly hygroscopic, meaning it readily absorbs moisture from the air. To prevent clumping, seal the container tightly after each use and store in a cool, dry place. Vacuum-packed packaging helps extend shelf life.

Q7: What is the shelf life?

A: 24–36 months in original sealed container under cool, dry conditions (≤25°C, ≤60% RH). Protect from moisture. Once opened, use within 12 months and keep container tightly sealed.

Q8: Can Alpha-GPC be used in clear liquid supplements?

A: Yes. Alpha-GPC is freely soluble in water, making it suitable for clear liquid formulations and ready-to-drink beverages.

Q9: Can Alpha-GPC be combined with Citicoline?

A: Yes - this is a common and synergistic combination. Both are choline sources with slightly different mechanisms. Alpha-GPC provides choline that crosses the blood-brain barrier, while Citicoline supports neuronal membrane synthesis. They are often used together in nootropic formulations.

Q10: Is Alpha-GPC safe during pregnancy?

A: Alpha-GPC is a naturally occurring compound, but high‑dose supplementation during pregnancy is not well studied. Always consult a healthcare provider before use during pregnancy.

Q11: Does Alpha-GPC have a fishy smell?

A: No. Unlike some choline sources (e.g., choline bitartrate), Alpha-GPC does not have a fishy odor, making it more suitable for flavored products and beverages.

Q12: Can Alpha-GPC be used in gummies?

A: Yes - with proper formulation. Its water solubility and neutral taste make it suitable for gummies and chewable supplements.

Test Item	Specification (99% Grade)	Test Result	Conclusion
Appearance	White to off-white fine powder	Conforms	Pass
Assay (HPLC)	≥99.0%	99.2%	Pass
Specific Optical Rotation	-2.4° to -2.8°	-2.7°	Pass
Water Content (KF)	<2.0%	1.9%	Pass
Heavy Metals (each)	≤0.5 ppm	Conforms	Pass
Lead (Pb)	≤0.5 ppm	<0.01 ppm	Pass
Total Plate Count	≤1,000 CFU/g	<100 CFU/g	Pass
E. Coli / Salmonella	Negative	Negative	Pass

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